ID A0A0A1U039_ENTIV Unreviewed; 471 AA.
AC A0A0A1U039;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Iron-dependent hydrogenase, putative {ECO:0000313|EMBL:ELP84258.1};
DE EC=1.12.7.2 {ECO:0000313|EMBL:ELP84258.1};
GN ORFNames=EIN_065030 {ECO:0000313|EMBL:ELP84258.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP84258.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP84258.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP84258.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NARF family.
CC {ECO:0000256|ARBA:ARBA00006596}.
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DR EMBL; KB207140; ELP84258.1; -; Genomic_DNA.
DR RefSeq; XP_004183604.1; XM_004183556.1.
DR AlphaFoldDB; A0A0A1U039; -.
DR EnsemblProtists; ELP84258; ELP84258; EIN_065030.
DR GeneID; 14883263; -.
DR KEGG; eiv:EIN_065030; -.
DR VEuPathDB; AmoebaDB:EIN_065030; -.
DR OrthoDB; 19999at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ELP84258.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 16..45
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 66..95
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 471 AA; 51710 MW; 6169C1140F73DC4D CRC64;
MPPKPSHQVT GLDHNDAICI DWSKCVGCQL CTTKCTFDVL EKGKPKSPPQ VHATRPNPEQ
QNTDLTRILL KDTDCVGCGH CTSVCNFGAL KPLDPFDAIM EAKKNGKKLV AMIAPSTRLG
VAECMGMPIG TTALAQLVLS LRKIGFDYVF DVDYGADKTT FDDHAEVMEM REKQTGPAIT
SCCPAWIELL EKDYPDLIPK TSTARSPIGC LAALIKRGWA NDVKIDPENL YTVGIMPCVA
KKVEAARPQI HQDYDASVTS VEVSNYFRAH LADEDKKFSE AREAEVEKTE EGLCDLPFRR
ISGGSNIFGK TGGVSETVFR VIAKNAGVPW NEVNITKEEM YKHASGSTMT KVIVDIKGTI
INGIVCHGGF AIRKACDMVR SGELTSKNCD VIEMMACLGG CLGGAGQPKI PPAKKAEMDK
RRVKLDDLDY KAEFKAATEN TDMLEFVKSH FDAHGEHEHL HTYFEARYPQ A
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