ID A0A0A1U0S2_ENTIV Unreviewed; 265 AA.
AC A0A0A1U0S2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Ribosomal RNA-processing protein 42 {ECO:0000256|ARBA:ARBA00042523};
GN ORFNames=EIN_327900 {ECO:0000313|EMBL:ELP86133.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP86133.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP86133.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP86133.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the RNase PH family.
CC {ECO:0000256|ARBA:ARBA00006678}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB207015; ELP86133.1; -; Genomic_DNA.
DR RefSeq; XP_004185479.1; XM_004185431.1.
DR AlphaFoldDB; A0A0A1U0S2; -.
DR EnsemblProtists; ELP86133; ELP86133; EIN_327900.
DR GeneID; 14885063; -.
DR KEGG; eiv:EIN_327900; -.
DR VEuPathDB; AmoebaDB:EIN_327900; -.
DR OrthoDB; 197480at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd11367; RNase_PH_RRP42; 1.
DR Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR015847; ExoRNase_PH_dom2.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11097:SF8; EXOSOME COMPLEX COMPONENT RRP42; 1.
DR PANTHER; PTHR11097; EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN; 1.
DR Pfam; PF01138; RNase_PH; 1.
DR Pfam; PF03725; RNase_PH_C; 1.
DR SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000313|EMBL:ELP86133.1};
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Hydrolase {ECO:0000313|EMBL:ELP86133.1};
KW Nuclease {ECO:0000313|EMBL:ELP86133.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 29..155
FT /note="Exoribonuclease phosphorolytic"
FT /evidence="ECO:0000259|Pfam:PF01138"
FT DOMAIN 186..249
FT /note="Exoribonuclease phosphorolytic"
FT /evidence="ECO:0000259|Pfam:PF03725"
SQ SEQUENCE 265 AA; 28881 MW; 14D818222317A7AD CRC64;
MYALSTSEVE FIKEGVSVNV RTDGRSVLQF REFRCERDVI DQANGSVRFF LGRTEVVVGI
KCELEEPQAT SSNEGRYTVL VRKSGADNVR DVSIEQMITV SLENAGKEML KKLCVSPGKL
CWVVYVDAIV VEDDGNVMDC VSLAVRAALL STLIPVVTVI SGDAEEVQID INKDNVQFIH
FEPSALPVCV SLVLLDEVYV VDPSHTEEMC SGGVLTTAVT ESGLVCGIQK GGVGSFKVNV
LYDMVMQAQT IGLKVIHDLD DILID
//
