ID A0A0A1U5A3_ENTIV Unreviewed; 598 AA.
AC A0A0A1U5A3;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Ankyrin repeat-containing protein, putative {ECO:0000313|EMBL:ELP86941.1};
GN ORFNames=EIN_315900 {ECO:0000313|EMBL:ELP86941.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP86941.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP86941.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP86941.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB206890; ELP86941.1; -; Genomic_DNA.
DR RefSeq; XP_004253712.1; XM_004253664.1.
DR AlphaFoldDB; A0A0A1U5A3; -.
DR EnsemblProtists; ELP86941; ELP86941; EIN_315900.
DR GeneID; 14885899; -.
DR KEGG; eiv:EIN_315900; -.
DR VEuPathDB; AmoebaDB:EIN_315900; -.
DR OrthoDB; 22721at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 31..221
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REPEAT 363..395
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 468..506
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 559..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 67658 MW; B3C720CF9A818C2F CRC64;
MTSSIDLFQR LFICPEGYKL MTEISRGMSA DSLQFVRDVI TFYEAHKQTM HFLSFLITDE
MQKATNGSMF RGNSFCSRCL TMYTFITMSN QYVVNFLKEP MDEIFSGKYG SLEVVPDIGT
AKILERIEKL KTCVSKFIAS IIETSELWPE SYRYICYVLY NETKKLNIIK PIQSIGGFLI
LRLICPAIVQ PHKTGFCLEK PSDEVMRNLV VVCKIVQCIS NATAPHEPLL KGLESYISQE
SLKLEAELER VFSVRPSKFS FVPIKDKDLE TAINGILSLW AENQKTVTTY LQENARQEFK
ELAEAVMLFN SKEYVSKKSV MKKKAKEDEA IQQLFAIARN GNVVDCESVL KKYPELIDCT
DVDMMTPLHY AFVFKNTEVV LYLLKNGASL YLKDAMGMNA LHYACQSNMV ETFDFFQSCD
YSEVGEVNEE GNTCLHYLSQ HQFGEKHEAF VQYLLCKDSA LLNVANYAGD TPLHFAVNCY
LSDTEIGTYT VKTLVKFGAN CTLENLKKIT PLMLAQQKGK IDIISLLVVD EVCKPISPQP
NLKLNAEIIR IRTNSAEVAA KKRGKSGSHK LPSSPRLLPA YLTKQTTQPI KSSPVVNK
//
