ID   A0A0A1U8G1_ENTIV        Unreviewed;      1230 AA.
AC   A0A0A1U8G1;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Actin, putative {ECO:0000313|EMBL:ELP91225.1};
GN   ORFNames=EIN_151120 {ECO:0000313|EMBL:ELP91225.1};
OS   Entamoeba invadens IP1.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP91225.1, ECO:0000313|Proteomes:UP000014680};
RN   [1] {ECO:0000313|EMBL:ELP91225.1, ECO:0000313|Proteomes:UP000014680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP1 {ECO:0000313|EMBL:ELP91225.1,
RC   ECO:0000313|Proteomes:UP000014680};
RA   Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC         Evidence={ECO:0000256|ARBA:ARBA00001836};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the actin family.
CC       {ECO:0000256|ARBA:ARBA00006752, ECO:0000256|RuleBase:RU000487}.
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DR   EMBL; KB206474; ELP91225.1; -; Genomic_DNA.
DR   RefSeq; XP_004257996.1; XM_004257948.1.
DR   AlphaFoldDB; A0A0A1U8G1; -.
DR   EnsemblProtists; ELP91225; ELP91225; EIN_151120.
DR   GeneID; 14890172; -.
DR   KEGG; eiv:EIN_151120; -.
DR   VEuPathDB; AmoebaDB:EIN_151120; -.
DR   Proteomes; UP000014680; Unassembled WGS sequence.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; ACTIN; 1.
DR   PANTHER; PTHR11937:SF387; ACTIN; 1.
DR   Pfam; PF00022; Actin; 1.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT   REGION          1..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          365..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          414..521
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          823..844
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..486
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1230 AA;  133286 MW;  0DEBCFF9322F5533 CRC64;
     MSTKAEKLKL KEEEKKKKEE EKRKKEEAKK KAEEEKKHKK EEEKRKKEEE KEKKKLEKEK
     KEQEKHHKGG HETEKQKVEK EKPKDEIKEK EKTEKDEKAK KEEEEKKQKE AAEAKAKKEE
     EEKVAKEKEA AEQKAKEEAA EKEKLEKEKA EKDAEEAKKK EEEAAKEKEA KEKAEKEEQE
     KAKEAAEQKA KTEVVENDKL NKEIIEKANE DVEAAKKKEE QEKQEADKKK AEEEAAKKKE
     EEEAAAKKAE EERVEKEKAE IEKANKEAAE KEKKEAEEAK ANEERIAKEK AEQEAKLEAE
     RVEKERLEKE KLEQDRLAKE KEEAEKLEKE RLEKEAAQKA EEERILKERA EAERIEKERL
     EREAAEKLEK ERLEQERVAK EKEEEERKAK ELAEKLAREE AEKLEKERIE KEVAAKLEQE
     RVAKEKAEAE RILKEKEESE RLEKERLEQE KIAKEKAEKE EQEKAVAEQK KKEEEEKAKK
     AAEEAQKKSQ PIPTLGNQPG LGMGMGLGAS QPGLGAKPPG LGQPGLGGMG LGAQPTPQPS
     LGMGMGAPGL GQPGLGMGAP QPGLGAKPPV LGQPGLGGMG QPGLGMGAPQ GGLGGMGQPG
     LGAKPPGLGL GAQPAGLGSQ STQQPGLGMG MGAPQPGLGG IGAAQPGLGV KPPGLGQPGL
     GGMGLGAQPT PQPSLGMGMG APGLGQPGLG MGAAQPGLGG MGQPGLGAKP PGLGLGAQPA
     GLGLGAQPSG LGLGAPSGGL GLGGAPTGLG LGGGQPTGLG LGGGQPAGLG LGGGLGMPGL
     GMGGGLGIGG MPAMGGMPGL GGMGGLPGMG MPAMGGMPDM GEIEKPEETA GGEQPKKRKR
     QKKKIMISQS AFFTHENEEK ANETLSRIPD DAVIVFDCGS SFIKVGTGGG EQPKKVIPNC
     YCKIDDEEAE NGVRYEFGYK AIDEDEGLVW PLDPRKETDW DGFFSVIQNI YQNELNGCDP
     AAHPVVMTEL PSMNEAATER LKVMMFNDLN VPFLKIVNPA LMALYAEGKE TGIVVEIGNR
     MQIVPAVDGY VIDSAIEKIK GNVSGLTEYM SRLLRACGYI YTTSAQMELV RAIKESVCYV
     ALDYDSEMKR KAKEVMKEFV VPGNEQASKF FQERFQCPEA LFQPEKVGLD TLGVPEMVFN
     TIKKCPLTSR RPLLQHIVLA GGSTLFEGLP ERLEKELKRL CTENKMNPRD VKIISLQNRK
     YLAWVGASLL AGMSTLQDDE TCTKDHYSNQ
//