ID A0A0A1U906_ENTIV Unreviewed; 674 AA.
AC A0A0A1U906;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Rap GTPase-activating protein, putative {ECO:0000313|EMBL:ELP91369.1};
GN ORFNames=EIN_154260 {ECO:0000313|EMBL:ELP91369.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP91369.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP91369.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP91369.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB206474; ELP91369.1; -; Genomic_DNA.
DR RefSeq; XP_004258140.1; XM_004258092.1.
DR AlphaFoldDB; A0A0A1U906; -.
DR EnsemblProtists; ELP91369; ELP91369; EIN_154260.
DR GeneID; 14890378; -.
DR KEGG; eiv:EIN_154260; -.
DR VEuPathDB; AmoebaDB:EIN_154260; -.
DR OrthoDB; 590187at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00030; C2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 1..117
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 154..269
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 450..669
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
SQ SEQUENCE 674 AA; 76692 MW; 9AAE7A296DACB9FC CRC64;
MIPTDSFVTI AVRIYSARNL PKADPTGLSD PYVVLTYTSF EKDRLTKKKK KTETVKTSLS
PIWNDAFVLN NVTPESFLIF NCFDWDNALK FSADDFLGKF KIMAERIPIN KNIVWRVPLK
DNDKSAGEIT FSTYAVPSSQ YIDTKENKKS LLMQTAIDQL NIDSIPLFVC RHQNLLQVMV
QKTEGFIDEK EKSSLYAQVC IGKQMLETIV YKKKGDPFWG SLLSFSYNKA NVIKIQIKDW
KMIKTNTVLG SVDIPLFDIT EDDMVIKSYP IKGSKGVLKC GVQIIKAENI TNLLPIECEA
DDEDDDWCKQ NIQPFEVFTD DVNTRGVVDT SLKDDYHFEM SEDDISNLLN EDVPIFNESY
FERPLKEGVC QSVNKKVFYN DVATDKGPIM IAVGDESGGL KRAVVISQFG NVKTYVTDLK
NIDNETMSVF GLKKDQVKMK ECDKSVWPKL IEFEERNQCH SYKIGLLYAK QGQRTEMEFL
SNTTPSPLCT EFYKLIGETV TLKGYTGYRG GLDVTSNTTG TTSIVSKYKG TEIMFHVATM
LQHVEEDPQH LDKKRHIGND VVVIIFKESN GKKDDEIDLN SFVTQFNHVF IIVTPTIVKG
SPFYKVCVCC KSAVQAFLPR FPPEKLFKRD EVFKEWLLCK AINGERSSIE SPQFIKSQRI
ARKGLLEVII NEVK
//
