ID A0A0A1U9X2_ENTIV Unreviewed; 487 AA.
AC A0A0A1U9X2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0000259|Pfam:PF00617};
GN ORFNames=EIN_521660 {ECO:0000313|EMBL:ELP91739.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP91739.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP91739.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP91739.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB206450; ELP91739.1; -; Genomic_DNA.
DR RefSeq; XP_004258510.1; XM_004258462.1.
DR AlphaFoldDB; A0A0A1U9X2; -.
DR EnsemblProtists; ELP91739; ELP91739; EIN_521660.
DR GeneID; 14890723; -.
DR KEGG; eiv:EIN_521660; -.
DR VEuPathDB; AmoebaDB:EIN_521660; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR Pfam; PF00617; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 269..407
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|Pfam:PF00617"
FT REGION 151..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 56481 MW; 7299F3ABA2719BDC CRC64;
MPIEKIFKVF SDGSFDTQKK YFIETVVRNR DLVFDPEGSI DPKFSKETFQ MVSVPPDIAF
ESIFFQIFSK ELLVQFLVVF SQTYTYDYFL SKLESKYNLF NVSTDVSNHE KKRLKEVAEL
YFEFYGTLMP LDIRQKFDDF IKRATELKNR VVHAKRSTPR SRTPRHSNSL ERQDDSIKKQ
ESVVDIENRE KSSLSKNRTQ SLLQITNTKV SLADKKVLVT TPKGFLSVDE IVKKVTTKIG
INSLLKEVVD YNEKTQKLLS NIEISLRLLA EQLYVTDLYL IKKVSIGDFL SESALSKKYS
QDLNSIISVF GKTVGVATNK TEIFEFFISV ACECLEISEY NFGYLIYCEF TSLSIKMEYA
EAFEHLGKAI KEKYNKLNNI FSISKKNTYF EHFDKVTTNK FPITSYMTVA VVASNVTKMK
DFSGEDYNHN FVSRMNIPGN VMVALYNVLK STIKYPFHKL IQKYLAMCLN EFESVQLWSQ
LLIFNCF
//
