ID   A0A0A1UAI0_ENTIV        Unreviewed;       661 AA.
AC   A0A0A1UAI0;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=5'->3' exoribonuclease, putative {ECO:0000313|EMBL:ELP92037.1};
GN   ORFNames=EIN_291360 {ECO:0000313|EMBL:ELP92037.1};
OS   Entamoeba invadens IP1.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP92037.1, ECO:0000313|Proteomes:UP000014680};
RN   [1] {ECO:0000313|EMBL:ELP92037.1, ECO:0000313|Proteomes:UP000014680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP1 {ECO:0000313|EMBL:ELP92037.1,
RC   ECO:0000313|Proteomes:UP000014680};
RA   Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KB206397; ELP92037.1; -; Genomic_DNA.
DR   RefSeq; XP_004258808.1; XM_004258760.1.
DR   AlphaFoldDB; A0A0A1UAI0; -.
DR   EnsemblProtists; ELP92037; ELP92037; EIN_291360.
DR   GeneID; 14891010; -.
DR   KEGG; eiv:EIN_291360; -.
DR   VEuPathDB; AmoebaDB:EIN_291360; -.
DR   OrthoDB; 167745at2759; -.
DR   Proteomes; UP000014680; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18673; PIN_XRN1-2-like; 1.
DR   Gene3D; 1.25.40.1050; -; 1.
DR   Gene3D; 3.40.50.12390; -; 2.
DR   InterPro; IPR027073; 5_3_exoribonuclease.
DR   InterPro; IPR041412; Xrn1_helical.
DR   InterPro; IPR004859; Xrn1_N.
DR   PANTHER; PTHR12341:SF41; 5'-3' EXORIBONUCLEASE 1; 1.
DR   PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR   Pfam; PF17846; XRN_M; 2.
DR   Pfam; PF03159; XRN_N; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT   DOMAIN          1..220
FT                   /note="Xrn1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03159"
FT   DOMAIN          280..363
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
FT   DOMAIN          359..581
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
SQ   SEQUENCE   661 AA;  76719 MW;  BE1703BAFFC7D2B9 CRC64;
     MGVPSFFAWV CSMCKDYTKY LPKNIQEDDL REQNHCGRDF DTFFIDFNGI VHNCSHPAHD
     VAPVSEAELF DRIFAQLDHY INYVRPRKLV YIAVDGVCPF AKIVQQRKRR YISARGNSGT
     SFDSNCITPG TPFMERLSVA LHAYVTNRMD TNLYWSSLSV ILSNPNVPGE GEHKIFDFLR
     KESKNTDFAN LKHCVYGMDA DLIMLTLASN LPFVYIIREE MEFTKPNIIC DVCHLNHRTN
     QHGKPVNLIL CDPNVLSTWL ITECAKTCEM KMEDISRVEL INDFVLITFL VGNDFLPKIP
     SLKVQSGGME IILKYYWPLF KEGKRLTNGI NINLHLLKEM FAKITTEESE LLKMVVRTTK
     KSQEVKQYDA GLYFDSADTI MIHTQGYHTR YYDTHFGKAN NTENFYKQIV GEYIEGLFWV
     FQYYTVGVPS WRWFYPEHYA PFAEDIYKYI DLNQEGLFEP DEPILPMEQL ISVLPPQSFN
     NIPSTLASLV VSKQSPILNY FNTTFRTDIN GEAKLFKGVP QLDFIDLSKI EELVAERMAE
     LKGREMRRNS RYGENLLYFT TEGEYSEIMP LFLDIQVKNF ETIQKVNEKI ESNPETILNE
     KEIGCLELTT NQRKILLGKL LPVVDTQFFV SPKLEYLLPE RGFLKKMMDK HVVNAYFRLL
     D
//