ID A0A0A1UCZ6_ENTIV Unreviewed; 952 AA.
AC A0A0A1UCZ6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Myotubularin, putative {ECO:0000313|EMBL:ELP90169.1};
GN ORFNames=EIN_406330 {ECO:0000313|EMBL:ELP90169.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP90169.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP90169.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP90169.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB206537; ELP90169.1; -; Genomic_DNA.
DR RefSeq; XP_004256940.1; XM_004256892.1.
DR AlphaFoldDB; A0A0A1UCZ6; -.
DR EnsemblProtists; ELP90169; ELP90169; EIN_406330.
DR GeneID; 14888966; -.
DR KEGG; eiv:EIN_406330; -.
DR VEuPathDB; AmoebaDB:EIN_406330; -.
DR OrthoDB; 20572at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR CDD; cd14507; PTP-MTM-like; 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF8; PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 530..936
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT ACT_SITE 749
FT /note="Phosphocysteine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR630564-1"
SQ SEQUENCE 952 AA; 109585 MW; A67E85E39E5DC747 CRC64;
MLAKSRSTRK AFCLTPQTPL NINDNLPLFK LSQTNFLFDK NVGKFTYNYS EYFNSDKMWY
FERVTDENGK TEITEMQFPN LPVSGVMDVL CFPYKNVNKL YLVPSESKTI IIQYDCFAVN
IVYNNTTKVS DLVHFFYQIL IMMELISDKY TSLGWMNYAL EWVDQRKRVK LLRGSSLIWG
MLNKKTVLTL RKIMRHGIIT EINEEDVIVE EEEIDYVVSN CFTNEVVCIV MIQNQQTFEM
IVDKTWTCQE LRQRIFIVSD LNDSTLKLYR RKGLYILEEM KEDNSLFEYV ENEGVLCVDV
MKTSNDVLLV ATQISFNSLP TRGTIPVEVF SLNNNSSFIK VDKKEVFKVC LTNTTTVSNV
LHSLCIGCDY YAFAHIDGNI TVISNCETVL CDSRVEKIGV VRAKTFPYLT SRLKRPKTYK
AISLMIPNME VMLYVEHNIL ITTYQTLIWK NGAFVRIPHN AVFSCIFCSL DESTDLLYFA
TKDIKQVLFK MGNSVTPRVL HVYTENKLLF PRTTSEIFAF RGIDITQSVE SRIVDPMFDF
QRIGVVGDKR FVIAENIFKT FSNDKSSLVF KCESYPEKVL LPFGNYDMGS LTNYRAKGRF
PIISWVGPNM QCLARSSQPL VGTFGQNVCD DDIQILESLK NLSPQKTIIV FDARPKLSAK
ATRIQGGGME TQLSYPFCTF VNLSMDGIKE IKQSFYSLLK VLFFGDKRSY TFVLDINNSK
WLQEIDQLIS YSIDIAKKLY NGSSILIHCR NGWDITCQLI SLVLIMLDPY YRTIEGFLVL
IQREWISAGH RFSLRTGCGV TWAIDPLPSL TSAFPNLKRV NQSSFREGLD SINDKATSPI
FFQFLEAVHL VLVNGKNNFQ FNDKLLIFLA DSLYDAKFSW FFENTVQHAS LKNTLSLPSY
ILSNVNDFLN PSFIAITTPY FPSFIMSNVS IWEDYYFRNN DFYAELSQCS SL
//
