ID A0A0A1UPS7_9HYPO Unreviewed; 970 AA.
AC A0A0A1UPS7;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=X797_009854 {ECO:0000313|EMBL:EXU97089.1};
OS Metarhizium robertsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=568076 {ECO:0000313|EMBL:EXU97089.1, ECO:0000313|Proteomes:UP000030151};
RN [1] {ECO:0000313|EMBL:EXU97089.1, ECO:0000313|Proteomes:UP000030151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXU97089.1,
RC ECO:0000313|Proteomes:UP000030151};
RA Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA Gibson D.M.;
RT "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT ARSEF 2575.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXU97089.1}.
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DR EMBL; JELW01000041; EXU97089.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1UPS7; -.
DR eggNOG; KOG2103; Eukaryota.
DR HOGENOM; CLU_005034_0_1_1; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000030151; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..970
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001991826"
FT TRANSMEM 937..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 736..966
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 970 AA; 104540 MW; ADCC0E2C51A8CD6B CRC64;
MRRTLQSALL LGLSSLAGAV FKDEVGDIDF HYSLVGLPQV ETTFFHRPRK EDKASLLYTL
GDVGVIGAIN PSNGELIWRQ QISHGIANGG GHLRAPEGEN WVTSAYGPKV QAWNALTGRN
IWDMEFKGVV KDLEILELTE SPRKDVLALF DEDGVTVLRR LHGALGTVVW EFRETSKDLP
VQVSTNIANI YVLSLHGSPG SYNLKVTSLD MATGARVDHW SVGNKGDIHG AEDVMFVGAN
SAAPIAAWAS RGLSKLSINV LGTKTKQEFT LPDGTETLRI HAPHLAQSQP HFLLHIGTKT
GHKAIVYHTD LKSGQVSKAY ELPHLSGPGA FSTSSDAANV YFTRITANDI SIVSSESHGI
LTSWPYLPKD GHAAVHAVSE VIKKAGGKEF AIRSAAVTDA DDWVLIKNGQ IDWTRHEGLS
GAVAAVWAEI PEAERLAEVL AEEAHANPVA AYIHRVNRHI ADLEHLPAYL ARLPQRIIDG
ISGADLTGHK DGLHRDTFGF SKIVVVATRR GRFYGLDTGR QGKILWSQAV FNVDPGESLA
IRGIVAKDAE SEVTVVGSNG ERATIASATG KILEAHQAGS FTKVASTAVI GDESSQWLLS
LGANGLPVPN MPIGTIPNDT VVLRDGSLGV KGVKFTAKDG EVIKDDIWQF QVGKGQKIVD
IASPPSHDPI SSIGRVLGDR KVAYKYFNPN TVVVAAIEEA TSTLLVHLLD IISGQVLASQ
VYNGVDSTKG LSCAMAENWY ACTFFGDYTV NDGTDRTIKG FQVAVSDLYE SPEPNDRGPL
GDAAEFSSLN PVDTPTGVPL PHVVSQAYVF SQQLKSLSVT QTLQGITSRQ LLAYLPDSNS
ILAVSRHIID PRRPVDRDPT SAEVEAEALM RYTPQFEIDG RGIVSHELDV LGVQEILATP
AVIESTSLLF AYGVDIFGTR AAPSGVFDIL GKGFNKVTLV GTVAALFVGV LFLAPVVRRK
QIDRRWEAFL
//
