ID A0A0A1V5E4_9HYPO Unreviewed; 649 AA.
AC A0A0A1V5E4;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=histone deacetylase {ECO:0000256|ARBA:ARBA00012111};
DE EC=3.5.1.98 {ECO:0000256|ARBA:ARBA00012111};
GN ORFNames=X797_002491 {ECO:0000313|EMBL:EXV04808.1};
OS Metarhizium robertsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=568076 {ECO:0000313|EMBL:EXV04808.1, ECO:0000313|Proteomes:UP000030151};
RN [1] {ECO:0000313|EMBL:EXV04808.1, ECO:0000313|Proteomes:UP000030151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXV04808.1,
RC ECO:0000313|Proteomes:UP000030151};
RA Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA Gibson D.M.;
RT "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT ARSEF 2575.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the histone deacetylase family. HD type 1
CC subfamily. {ECO:0000256|ARBA:ARBA00006457}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXV04808.1}.
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DR EMBL; JELW01000002; EXV04808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1V5E4; -.
DR eggNOG; KOG1342; Eukaryota.
DR HOGENOM; CLU_007727_0_0_1; -.
DR OrthoDB; 1327607at2759; -.
DR Proteomes; UP000030151; Unassembled WGS sequence.
DR GO; GO:1902494; C:catalytic complex; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd10004; RPD3-like; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR003084; His_deacetylse_1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF13; HISTONE DEACETYLASE HDAC1; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR PRINTS; PR01271; HISDACETLASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853}.
FT DOMAIN 43..332
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 388..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 72218 MW; 7EE5D74FAFA7CA20 CRC64;
MGDSNLAQAQ AQLGSVALNG SSAKKVAYFY DSDIGNYAYV TGHPMKPHRI RLAHSLIMQY
NLYQKMEIYR AKPATRGEMT QFHTDDYIDF LQKVTPDNMD SYMREQGKYN VGDDCPVFDG
LFEFCGISAG GSMEGAARLN RQKCDIAVNW AGGLHHAKKC EASGFCYVND IVLGILELLR
FMKRVLYIDI DVHHGDGVEE AFYTTDRVMT VSFHKYGEYF PGTGELRDIG IGQGKNYSVN
FPLRDGITDQ TYKSIFEPVI ESVMKYYQPE AVVLQCGGDS LSGDRLGCFN LSMDGHANCV
NYVKSFGLPT LVLGGGGYTM RNVARTWAYE TGVLVGQEMD RTLPYNEYYE YYAPDFELNV
RASNMENSNS REYLDKITAA VIDNLRQTGP APSVQMQDVP RKPFGGMTDE EEAELDDLDE
DENKDVRMTE HRWDKHVENG AEFEASDDDE MAAANGATRS NGNKGTFNDF KSADAAEDSR
SKSPREKHDD NSKEAVEAET HDVNDDTIED VGAMEEQENQ AAEQEEKEDQ DLKKNKVDAD
GDVGMTYSSV ADEATIKKEE GEPESVPEDE KEPERPTEEK PSVAEPDKPA EAEGATEVKA
SDKPAVDQVS EEPAEKEGEA QATTEAETEP MEVDDKEKSE DKAEDDSSK
//
