ID A0A0A1V5R1_9HYPO Unreviewed; 752 AA.
AC A0A0A1V5R1;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ion channel {ECO:0000313|EMBL:EXV05592.1};
GN ORFNames=X797_000308 {ECO:0000313|EMBL:EXV05592.1};
OS Metarhizium robertsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=568076 {ECO:0000313|EMBL:EXV05592.1, ECO:0000313|Proteomes:UP000030151};
RN [1] {ECO:0000313|EMBL:EXV05592.1, ECO:0000313|Proteomes:UP000030151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXV05592.1,
RC ECO:0000313|Proteomes:UP000030151};
RA Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA Gibson D.M.;
RT "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT ARSEF 2575.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|RuleBase:RU003857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXV05592.1}.
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DR EMBL; JELW01000001; EXV05592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1V5R1; -.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_013394_0_0_1; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000030151; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 58..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 225..297
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 386..462
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..664
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 85696 MW; E4A0E075F27CEDC3 CRC64;
MDDGKHGKAI EHHASDLDNS LSKQMSRQQL QHKRSRETRF QNDLAHLIPS RWWFASSAFP
MIAATLGPVA SAFSICALGS QWRQKLVPGQ NVDDAVFIQD PAWLTIVNAI QLAVALVSNA
FLLLNMTKRV RFSIAQPITI IGWYISAICL LSLNATAAGP LQYNLDPPQD YIWSQAFYYG
IWAAILYFVD ASLMAVTFWG ASSGHYPKDF NLTRSQRTLM LQTILFLMYL LLGALIFSKI
ENWRYLDAVY WADVTLFTVG FGDFAANTTL GCALLIPYAL IGVISLGLVI SSIRSMILER
GRRRLDARME EKNRRRFIRT MTKSGHDEIL SPIDDDTVSN WGPENAGLPQ NEFDRRKTEF
LLMRKIQQQA SIRRKWMAMA ISTGVWILLW LVGAVIFVSA EEPYQQWNYF DAFYFCFISL
MTIGYGDRTP NSNAGKSFFV FWSLLALPTM TVLISNAGDT VVKFVTDATI RIGNITILPG
EEGFTGNAKY VANRVSFGRL FRSATITIRE HEREKTIHKK AEDLTGFDPK DVKDTEKQQN
ESSHSGGSAS HGHREDDEER QGKHKLCQKT EIPAGRPSLA QVQDRLDDLP IGTELHLLLV
KEIQTVSQHL REPEPRRYTF EEWAWYLALI GEDERDPLNH RKVLSKVKHR RARRHKHKHH
NRHRDKADQG RDPPQDEVAE TIRAPRPSMQ LAAPIPAQLP DTDARLKWSW VGSRSPLMGG
QEESEWILDK LMERLEESLW ETKIDEDDAN SP
//
