ID A0A0A1VD26_9BURK Unreviewed; 308 AA.
AC A0A0A1VD26;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Membrane-fusion protein {ECO:0000313|EMBL:GAD21147.1};
GN ORFNames=AVS7_00907 {ECO:0000313|EMBL:GAD21147.1};
OS Acidovorax sp. MR-S7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=1268622 {ECO:0000313|EMBL:GAD21147.1};
RN [1] {ECO:0000313|EMBL:GAD21147.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-S7 {ECO:0000313|EMBL:GAD21147.1};
RX DOI=10.1128/genomeA.00412-13;
RA Miura T., Kusada H., Kamagata Y., Hanada S., Kimura N.;
RT "Genome Sequence of the Multiple-beta-Lactam-Antibiotic-Resistant Bacterium
RT Acidovorax sp. Strain MR-S7.";
RL Genome Announc. 1:e00412-13(2013).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; DF238899; GAD21147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A1VD26; -.
DR STRING; 1268622.AVS7_00907; -.
DR eggNOG; COG0845; Bacteria.
DR Proteomes; UP000030646; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000030646};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 2..206
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 207..274
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT REGION 286..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..78
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 308 AA; 32479 MW; E6BFC334816BC0FE CRC64;
MVKAGQVLYE IDPTLYQSAV NEATASLRNA QAVVAAAEAK SRRYGELVDI EGVSRQEVDD
AKAAHEQARA AVEQQRAVLE TARVNLAYTQ VRAPIGGRIG KSTVTPGALV TASQADPLAT
IRKLDPMYVD VTQSSADLLR LRQVLSTGGL RPADAAIKMV LEDESAYAQP GRLKFSEVAV
DESTGTVTLR AEFPNPDGVL LPGMYVRAVL TEAVEPEAIM APQQGITRDP KGGATALVLN
AENKVVPRAV TTRRSIGDQW LVASGLSEGD RLIVQGLNKV KAGDTVNPVT VDPKAPAAPA
RPATAGGR
//
