ID A0A0A1VK14_9BURK Unreviewed; 693 AA.
AC A0A0A1VK14;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=AVS7_03663 {ECO:0000313|EMBL:GAD23903.1};
OS Acidovorax sp. MR-S7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=1268622 {ECO:0000313|EMBL:GAD23903.1};
RN [1] {ECO:0000313|EMBL:GAD23903.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-S7 {ECO:0000313|EMBL:GAD23903.1};
RX DOI=10.1128/genomeA.00412-13;
RA Miura T., Kusada H., Kamagata Y., Hanada S., Kimura N.;
RT "Genome Sequence of the Multiple-beta-Lactam-Antibiotic-Resistant Bacterium
RT Acidovorax sp. Strain MR-S7.";
RL Genome Announc. 1:e00412-13(2013).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; DF238953; GAD23903.1; -; Genomic_DNA.
DR RefSeq; WP_024001777.1; NZ_DF238953.1.
DR AlphaFoldDB; A0A0A1VK14; -.
DR STRING; 1268622.AVS7_03663; -.
DR eggNOG; COG1298; Bacteria.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000030646; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:GAD23903.1};
KW Cilium {ECO:0000313|EMBL:GAD23903.1};
KW Flagellum {ECO:0000313|EMBL:GAD23903.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000030646};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 209..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 242..268
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 289..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 693 AA; 74054 MW; B5EFBBA0D21CD1DA CRC64;
MTPSMNSVRQ WAGDNRSALQ GLSAPLLVVA ILALMVLPIP PWMLDTFFTL NIAVALMVMM
VAAYMVKPLD FAAFPSVLLL TTLMRLSLNV ASTRVVLLEG HTGPGAAGAV IEAFGHFLIG
GNFAVGLIVF AILVVINFVV VTKGAERIAE VSARFTLDAM PGKQMAVDAD LNAGLIDDKE
AKRRRAEVQE EANFFGSMDG ASKFVRGDAI AGILILVINI IGGFAIGMLQ HGLSASDAAN
SYILLAVGDA LVAQIPGLLI SVAAAMVISR VGKEEDMGRQ IVQQLFMSPR VLGVTAGILI
LLGLIPGMPH AVFLVMGSGI GYGAWVLMQR QNRPPPVEEA PGPVADGEAS WDDLQPVDLL
GLELGYRLIA LVDKNRQGDL LTRIKGVRRK FAQEVGFLPP AVHVRDNLEL KPSAYRITLR
GVVVGEGEAF PGMFLAINPG GISTPLIGTP TTDPAFGLPA HWIDAGQKEA AQMAGFTVVD
PETVMATHLS HLMQVQASKL LSRTETQQLV EHVARLAPKL IEEVVPKMVS ITTFQKVLQL
LLEESVHIRD IRTIIETLAE HAGSTQDPVE LARRVRIALS PAIVQQIYGP TRELSVIAIE
PGLERLLMQA LGNAGGPALD PGVADLLTHK AAEVAMKQEE LGMPACLLVP DQIRGAIARL
VRRVAPRLQV LAHSEIPETH TIRIGPILKG ATS
//
