ID A0A0A2DTX6_9PORP Unreviewed; 399 AA.
AC A0A0A2DTX6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=HQ37_04715 {ECO:0000313|EMBL:KGN70026.1};
OS Porphyromonas sp. COT-239 OH1446.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1515613 {ECO:0000313|EMBL:KGN70026.1, ECO:0000313|Proteomes:UP000030150};
RN [1] {ECO:0000313|EMBL:KGN70026.1, ECO:0000313|Proteomes:UP000030150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COT-239 OH1446 {ECO:0000313|Proteomes:UP000030150};
RA Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT "Porphyromonas sp. COT-239_OH1446 Genome sequencing.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGN70026.1}.
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DR EMBL; JRAO01000016; KGN70026.1; -; Genomic_DNA.
DR RefSeq; WP_036881029.1; NZ_JRAO01000016.1.
DR AlphaFoldDB; A0A0A2DTX6; -.
DR STRING; 1515613.HQ37_04715; -.
DR eggNOG; COG3579; Bacteria.
DR OrthoDB; 9814054at2; -.
DR Proteomes; UP000030150; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR004134; Peptidase_C1B.
DR Pfam; PF03051; Peptidase_C1_2; 2.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:KGN70026.1}; Hydrolase {ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|PIRNR:PIRNR005700};
KW Reference proteome {ECO:0000313|Proteomes:UP000030150};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|PIRNR:PIRNR005700}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..399
FT /note="Aminopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001986579"
FT ACT_SITE 53
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 334
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 355
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 399 AA; 45260 MW; 38389640DFAFA9F0 CRC64;
MKKILLLATL LCVAPLWGQS KSKKKDPNEK NVFTVVKELG RSSIKDQANS GTCWSYSGQG
FIEEELIRIG KPQYDLSEMF VVSHSYRDKA RKFVRLHGFL NYEQGGSFYD VLYVLKHYGA
VPRSVMPGLN YGTTRNAHNE LAETSKAFLN AVIKNPNGKL STAWWSAYTG IIDSYLGELP
EKFNWNGKEY TPKSYAAEMG INPDDYVSLT SYSHQPFYSK FALEIQDNWR WSESYNLPID
ELMQVMDSAI DHGYSFAWGA DVTEKGFTRD GLGVLADLDE VQSKGSDFAR WFGSGSDKKA
ALDKIIRRAD CPEIEPTQAY RQMGYDNYQL TDDHGMTIYG KAVNQNGRKF FMVKNSWGET
GEYKGVWYVS YNYAKGRTMN IVLHKDAIPE AIAKKLGLK
//
