ID A0A0A2EPF1_9PORP Unreviewed; 720 AA.
AC A0A0A2EPF1;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Tetracycline resistance protein TetQ {ECO:0000256|ARBA:ARBA00013902};
GN ORFNames=HW49_06155 {ECO:0000313|EMBL:KGN79577.1};
OS Porphyromonadaceae bacterium COT-184 OH4590.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae.
OX NCBI_TaxID=1517682 {ECO:0000313|EMBL:KGN79577.1, ECO:0000313|Proteomes:UP000030107};
RN [1] {ECO:0000313|EMBL:KGN79577.1, ECO:0000313|Proteomes:UP000030107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COT-184 OH4590 {ECO:0000313|Proteomes:UP000030107};
RA Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT "Porphyromonadaceae COT-184_OH4590 Genome sequencing.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGN79577.1}.
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DR EMBL; JRAN01000046; KGN79577.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2EPF1; -.
DR eggNOG; COG0480; Bacteria.
DR OrthoDB; 9801591at2; -.
DR Proteomes; UP000030107; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04170; EF-G_bact; 1.
DR CDD; cd01434; EFG_mtEFG1_IV; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR047872; EFG_IV.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF7; ELONGATION FACTOR G-LIKE PROTEIN; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 2.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:KGN79577.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:KGN79577.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030107}.
FT DOMAIN 7..280
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 720 AA; 80081 MW; CBB19102114151B6 CRC64;
MKIYKSSEIR NVSLLGSAGT GKTTLVEAML FESGAIKRKG TIEGKNTVSD YFPVEQEYGY
SVLPTIITAE WANKKINIID CPGADDFVGG AITSLAVTEQ SVILVNAQYG VEVGTHNHFR
YADKFRKPVI FAVNQLDREM ADFDKTFEQL RESFGGKVAL VQYPVNAGTA FNAVIDVLKL
KMYRWKPEGG QPEELDIPDS EKAKAEELHA ALIEAAAEND ETLMERFFEQ GSLKEEEIFE
GIHKGLINCG IYPVLCLCGG KSMGVRRLME FLGAVAPSPV EMTAPVTTGG VEVKPDANAP
TSLFFFKTSV EPHIGEVLYF KVISGKIKGG DDMTNVSRNG NKERISQIFS VAGQTRTQVD
EMVAGDIGAT VKLKDVRTGN TVNGKDVDWV FPEVNYPAPK YRRAIKAKNE GEDEKLGEIL
NRLHAEDPTW VIERSKELRQ TILSGQGEFH LRTLKWRVEN LDKIMIEYSE PRIPYRETIT
KAARADYRHK KQSGGAGQFG EVHLIIEPYQ EDVPAQEVYK FNGQEYKISV RDTQEIDLDW
GGKLIFINSI VGGSIDARFM PAILKGIMDR MEQGPLTGSY ARDVRVIVYD GKMHPVDSNE
ISFRLAGRNA FAQAFKEAGP KLLEPIYDLD VLVPSDRMGD VMSDLQGRRG MVLGMNSERG
FEHLKAKVPL KEVSSYSTAL SSISGGRASF AMKFSSYELC PTDVQDKLIK EYEATQNDEE
//
