ID A0A0A2ETS7_9PORP Unreviewed; 674 AA.
AC A0A0A2ETS7;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=HW49_04365 {ECO:0000313|EMBL:KGN81117.1};
OS Porphyromonadaceae bacterium COT-184 OH4590.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae.
OX NCBI_TaxID=1517682 {ECO:0000313|EMBL:KGN81117.1, ECO:0000313|Proteomes:UP000030107};
RN [1] {ECO:0000313|EMBL:KGN81117.1, ECO:0000313|Proteomes:UP000030107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COT-184 OH4590 {ECO:0000313|Proteomes:UP000030107};
RA Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT "Porphyromonadaceae COT-184_OH4590 Genome sequencing.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGN81117.1}.
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DR EMBL; JRAN01000030; KGN81117.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2ETS7; -.
DR eggNOG; COG1480; Bacteria.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000030107; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030107};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 468..612
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 674 AA; 76878 MW; 5E394098626CDDC7 CRC64;
MGLKLSRANF KYKHTRILIY ILMFVATTFL IFKMFPQRTH FDKKYEVGKP WHYELLTAPF
DFPIYKTDSE LRQERDSIKR RFTPYYTIDA NKAIDAIDRF KADTTIKGNI RYHLQRALQN
IYKRGVVTQT DYDDFKKSAM TSINVSDSSN IWRKIEVANI FTPTSALGYI SSNYPITAAT
LDSLNISRFV EVSLNIDKNK SEHTLNELLK SIPLSNGMVQ AGERIIDRGE IVKQEQGKIL
NSLKKEYADN TPNQDNKLVA LADIFMIAIL LALFVIYVVL FRPEFIRIKN AVFIVVMILI
VVCGASLIMG YNSDIINVVP FALMAIIIRI FFDSRTALFI HNIVVLIVSL FVPSPFLFLM
LHIPAGMIAV STLKQLTHRG QLVQSAIFIF ITYAFIYSFC TIIETGLFTF AWQHYLIFAV
NALLLLFAYI LIYIFEKLFG YLSDVTLVEL SNINNKLLMD FSAKAPGTFQ HVIQVSTLAA
AIAQKINANM LLARTGALYH DIGKMKNPMC FIENQVSGFN PLNDMTCQEA ARVIIAHVDD
GVKIAEQNSL PKQIINFIKS HHAKSLVRYF YITEQKENPN VEIDKSLFSY NGRYPDTKEE
AIVMMADAVE AASRSLKEYN ETTIGALVDD IINTQVADQS FKESPLTFKH IDIAKNVLKE
KLINIYHSRI EYPK
//
