ID   A0A0A2EWS6_9PORP        Unreviewed;       949 AA.
AC   A0A0A2EWS6;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:KGN81965.1};
GN   ORFNames=HQ41_09185 {ECO:0000313|EMBL:KGN81965.1};
OS   Porphyromonas sp. COT-290 OH860.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=1515615 {ECO:0000313|EMBL:KGN81965.1, ECO:0000313|Proteomes:UP000030116};
RN   [1] {ECO:0000313|EMBL:KGN81965.1, ECO:0000313|Proteomes:UP000030116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COT-290 OH860 {ECO:0000313|Proteomes:UP000030116};
RA   Wallis C., Deusch O., O'Flynn C., Davis I., Jospin G., Darling A.E.,
RA   Coil D.A., Alexiev A., Horsfall A., Kirkwood N., Harris S., Eisen J.A.;
RT   "Porphyromonas sp. strain:COT-290_OH860 Genome sequencing.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGN81965.1}.
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DR   EMBL; JRAR01000078; KGN81965.1; -; Genomic_DNA.
DR   RefSeq; WP_044190623.1; NZ_JRAR01000078.1.
DR   AlphaFoldDB; A0A0A2EWS6; -.
DR   eggNOG; COG0612; Bacteria.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000030116; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030116};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..949
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001998489"
FT   DOMAIN          71..194
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          214..400
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          700..879
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   949 AA;  106104 MW;  9903A63745C294B0 CRC64;
     MNVLNKLRRS LVALSTGALL AVTTLASAQQ LPPPLPADTA LRMGQLENGL TYFIRKNALP
     EGRADFYIAQ KVGSMQEEDS QSGLAHFLEH IAFNGTKNFP GKGMINWLET IGVRFGFGIN
     AYTSFDETVY TLINVPVERQ SVVDSCLLIL HDWSNAISLE DKEIDNERGV IQEEWRSRDS
     GNQRIAEKAF EAAFPGNRYG KRMPIGSMDI VRNFKYQELR DYYKKWYRPD LQALIIVGDI
     DVDHVEATIK KQFADVPKPV NPAERVYIAV EDNDAPISII ATDPEGVGTR ISIAFKTDVT
     PAEIRATAFG VAEHYIKSVI TAMINDRFEE IWKKPNAPFI AASANFGPYF QVAKTKDAWT
     FSAVAADGKY EPALQALVAE IERVRQHGFT EGELKRAKKN FMVGMKTTYN ERNKRKNGSF
     TSVYVDYFIN GGTLADIDVL YPIYEQFAEL LPLAQINAMA QELLGEKNIA ISLTGPEKPE
     FKYPTKDELV SQFLNARKQP VEVYKEPVSD EKLMKKLPKA GKIVKEDKQG QYGSTVWTLS
     NGVKVIYKST DFKEDQILMS AVRHGGLASF PKADPTELRM INDISSLGGI AEFDETALGR
     VLTGRVVSLN ASLGQITDGL SGNSSKDDLE TLLQLIHLSF TAPRLDNQAY EAFREKMVNL
     IETQKSNPMS SVGDSISAAI YPGNKLFQSV TVEELNAMSY ESAMKLYNER MTNAKDFQFF
     FVGNVAPEKL RPLVELYIAS LPVKKNLDTK PMESRLPSLR KGVFTNHYTK KQSTPAGLVF
     DFISGKLPYS QRNAMIMSIV GEVLNQVYTA TIREEEGGTY GANASASVIR YPEGEAKLQV
     TFQTDPAKAH QLNKIVYAEI DRLVQEGAKA ENFDKVLENM KKSHATSLKE NSYWLSQLSN
     YYFRGTDNVS QYEATLGSIK REDLAPLVKQ LLDQKNRVEV MLMPEAEAK
//