ID A0A0A2I5Q6_PENEN Unreviewed; 1106 AA.
AC A0A0A2I5Q6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Peptidase M16, core {ECO:0000313|EMBL:KGO54565.1};
GN ORFNames=PEX2_070980 {ECO:0000313|EMBL:KGO54565.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO54565.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO54565.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO54565.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO54565.1}.
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DR EMBL; JQFZ01000221; KGO54565.1; -; Genomic_DNA.
DR RefSeq; XP_016596936.1; XM_016744369.1.
DR AlphaFoldDB; A0A0A2I5Q6; -.
DR STRING; 27334.A0A0A2I5Q6; -.
DR MEROPS; M16.008; -.
DR GeneID; 27679789; -.
DR HOGENOM; CLU_004639_1_2_1; -.
DR OrthoDB; 129328at2759; -.
DR PhylomeDB; A0A0A2I5Q6; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR InterPro; IPR032632; Peptidase_M16_M.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 2.
DR Pfam; PF16187; Peptidase_M16_M; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 33..203
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 230..408
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT DOMAIN 414..702
FT /note="Peptidase M16 middle/third"
FT /evidence="ECO:0000259|Pfam:PF16187"
FT DOMAIN 709..886
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT REGION 113..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1106 AA; 125940 MW; 18566402D17BBEA0 CRC64;
MAQIERITEN LEKPELDDRS YRVIRLPNKL EALLVHDPDT DKASAAVNVN VGNFSDEDDM
PGMAHAVEHL LFMGTKKYPK ENAYNQYLAS HSGSSNAYTA ATETNYFFEV SATGDSSAPK
SSGDSTPAET NDNNGVATNG NGSDGKSPLY GALDRFAQFF VAPLFLESTL ERELQAVDSE
NKKNLQSDLW RLMQLNKSLS NPKHPYSHFS TGNLQTLKED PQKRGLEVRS EFIRFYEKHY
SANRAKLVVL GRESLDTLEQ WVSELFSDVE NKNLAQNRWD DVQPFTEKDM CTQVFVKPVM
DTRSMDMYFP FLDEEDLHDT QPSRYISHLI GHEGPGSVLS YLKAKGWANG LSAGAMPVCA
GSAFFTISVR LTPEGLKQYQ EVANVVFEYI AMIKQRDPEQ WIFDEMKNLA EVDFRFKQKT
PASRFTSRLS SVMQKSLPSE WLLSGSLLRR FDSDLIKKAL SYLRADNFRL VVVSQEFPGT
WDQKEKWYGT EYKVEKIPQE FLGGLQKALE STEATRTSNV HMPHKNEFVP TRLSVEKKEV
AEPTNTPKLI RHDDRVRLWF KKDDRFWVPK ATVEVTLRNP LVWATPANLI KTKLYSELVR
DSLDEYSYDA ELAGLDYHLS ANILGLDISV SGYNDKMSAL LDKVLNTMRG LVVNQDRFHI
IKERLTRAFR NAEYQQPYYQ VGDYTRYLLA ERSWVNEQYL EELEHVECDD VVNFFPQLLE
QTHIEVLAHG NLYKEDALRM TDSIEKILGG RPLPPSQWYL RRNMTLPPGA NYVYPRSLKD
PANVNHCIEY YLYIGLFSDD VLRSKLQLFA QLTDEPAFDQ LRSKEQLGYV VWSGARYNAT
TLGYRVIIQS ERTAQYLESR IETFLRQFGP ILEKMPEEEF EGHKRSVVNK RLEKLKNLSS
ETGRYWSHVG SEYFDFLQHE TDAANVRALT KADLIAFYQQ YIDPSSATRA KLAIHMNAQS
GAQVEAPKPA EQRTRLVEVV TKHLEAAEFT VDSARFAKAL DEVDTTAADK SQVIFAMKNF
LETETGLSQK KIEPVLETLD EKLSSQLKEL GLDSSSDTQG AANGNGEAQK AVVITDVPTF
KARLPVSTGP VPVTDLSEYE DFDAKL
//
