ID A0A0A2JWG4_PENEN Unreviewed; 213 AA.
AC A0A0A2JWG4;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 13-SEP-2023, entry version 34.
DE RecName: Full=GTP-binding nuclear protein {ECO:0000256|RuleBase:RU363057};
GN ORFNames=PEX2_053800 {ECO:0000313|EMBL:KGO59802.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO59802.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO59802.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO59802.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- FUNCTION: GTP-binding protein involved in nucleocytoplasmic transport.
CC Required for the import of protein into the nucleus and also for RNA
CC export. Involved in chromatin condensation and control of cell cycle.
CC {ECO:0000256|RuleBase:RU363057}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU363057}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ran family.
CC {ECO:0000256|ARBA:ARBA00008028, ECO:0000256|RuleBase:RU363057}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO59802.1}.
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DR EMBL; JQFZ01000089; KGO59802.1; -; Genomic_DNA.
DR RefSeq; XP_016600905.1; XM_016742654.1.
DR AlphaFoldDB; A0A0A2JWG4; -.
DR STRING; 27334.A0A0A2JWG4; -.
DR GeneID; 27678073; -.
DR HOGENOM; CLU_041217_13_0_1; -.
DR OrthoDB; 5471873at2759; -.
DR PhylomeDB; A0A0A2JWG4; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00877; Ran; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002041; Ran_GTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24071:SF0; GTP-BINDING NUCLEAR PROTEIN RAN; 1.
DR PANTHER; PTHR24071; RAN GTPASE; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00627; GTPRANTC4.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51418; RAN; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363057};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU363057};
KW Protein transport {ECO:0000256|RuleBase:RU363057};
KW Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW Transport {ECO:0000256|RuleBase:RU363057}.
SQ SEQUENCE 213 AA; 24192 MW; DD57EE16EB7BC472 CRC64;
MAETPTFKLV LVGDGGTGKT TFVKRHLTGE FEKKYIATLG VEVHPLNFNT NYGAIQFDVW
DTAGQEKFGG LRDGYYINGQ CGIIMFDVTS RITYKNVPNW HRDLVRVCEN IPIVLTGNKV
DVKERKVKAK TITFHRKKNL QYYDISAKSN YNFEKPFLWL ARKLVGNPQL DFVAGIALAP
PEVTVDEKQL EAYRKEMEEA ANQPLPDEDD ADL
//
