ID A0A0A2JXJ6_PENEN Unreviewed; 1539 AA.
AC A0A0A2JXJ6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=ABC transporter, integral membrane type 1 {ECO:0000313|EMBL:KGO59373.1};
GN ORFNames=PEX2_073280 {ECO:0000313|EMBL:KGO59373.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO59373.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO59373.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO59373.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO59373.1}.
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DR EMBL; JQFZ01000096; KGO59373.1; -; Genomic_DNA.
DR RefSeq; XP_016600569.1; XM_016744598.1.
DR STRING; 27334.A0A0A2JXJ6; -.
DR GeneID; 27680018; -.
DR HOGENOM; CLU_000604_27_3_1; -.
DR OrthoDB; 3295317at2759; -.
DR PhylomeDB; A0A0A2JXJ6; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IEA:UniProt.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18595; ABC_6TM_MRP1_2_3_6_D1_like; 1.
DR CDD; cd18603; ABC_6TM_MRP1_2_3_6_D2_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF456; BILE PIGMENT TRANSPORTER 1-RELATED; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 968..989
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1009..1036
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1095..1121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..588
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 624..849
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 969..1253
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1290..1525
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 854..875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1539 AA; 171107 MW; F6282F0AA264D209 CRC64;
MLDGQSQVVL EASRPGHLLH SLGSALDSRR QPFCTDSEGW GPVSSLRFDL TPCFLDAVVA
VVAVWGTLSG LGALWLLLRK RIPQPVSKNW HFYTKLAVLA ALIVVTALQA AIQVESDPKR
FWSDFRFWSS VLTIISLGVI TSVQYLEHWR SRQPNGVVLF YWLFFIIAYA VKLRSLVARK
EYVGQLPYFI CFNISLGLAL FEFVLEYFVP KKQSAYDALG DEDECPYNYA DIFSVLTFGW
MTPMMKYGYK NYLTQDDLWN LRSRDTTRAT GNALKEAWDE QLEKKNPSLW TALFKAFGAP
YVRGAIIKSG SDVLAFVQPQ LLRLLIAFID SYRRPDPQPI IRGVAIALSM FVVSVCQTSF
LHQYFQRAFD TGMRVKSALT AMIYAKSLKL SNEGRSTKTT GDIVNHMAVD QQRLADLTQF
GTQLISAPFQ ITLCMISLYQ LLGASMFAGI GVMILMIPLN GVIARMMKKL QIIQMKNKDS
RTRLMTEILN NIKSIKLYAW NTAFMNKLSH IRNDLELNTL RKIGATQSVA NFTWQSTPFL
VSCSTFTVFV LTNDKPLTTE IVFPALTLFN LLTFPLSILP MVITSIIESS VAVTRLVEYF
TAEELQTNAV ILQDAVAHPG DESVRVRDAT FTWNRHSGET VLENIDLSAR KGELSCIVGR
VGAGKSSLLQ SLLGDLWKNQ GEVVVRGRIA YVAQAPWVMN ASVRENIVFG HRWDPSFYDL
TVEACALLDD FKNLPDGDQT EVGERGISLS GGQKARLTLA RAVYARADIY LLDDILSAVD
QHVGRHIINR VLGKNGLLGG KTRILATNAI TVLKEADFIG LLRDKTIIEE GTYEQLMAMK
GEISNLVRST MVDSDDEGTV SGSEDLASPE SSVTTTIIQN SGASDSEEAE QLGDLIPIRA
GGGGEARRRT STVTLRRAST VSWQGPRRKL GDEENVLKSK QTQEVSEQGK VKWGVYLQYA
KDSNVMAVVV YLVAMMAAQT AQVVGNFWLK RWTEWNEAHG TNAQVGKFIG VYLGLGLGSS
LLVIVQNLIL WIFCSIEASR KLHERMAFAI FRSPMSFFET TPSGRILNRF SSDIYRVDEV
LARTFNMLFA NSARAMFTVI VISATTPAFL IFVLPLGYIY LSYQKYYLST SRELKRLDSV
TRSPIYAHFQ ESLGGISTIR AYRQENRFAL ENEWRMDANL RAYFPSISAN RWLAVRLEFI
GSIIILASAG LAITSVATGT KLAPGMVGLA MSYALQITQS LNWIVRQTVE VETNIVSVER
VLEYANLPSE APEVIFKRRP AIGWPAQGAV EFNNYSTRYR PGLDLVLKDI SLNIKPKEKI
GVVGRTGAGK SSLTLALFRI IEGVEGNINI DGLDVSTIGL TDLRGRLAII PQDPAMFEGT
LRDNLDPRHV HDDTELWSVI DHARLKDHVS RMDGQLDAQI QEGGSNLSQG QRQLVSLARA
LLTPSNILVL DEATAAVDVE TDALLQRTLR SSIFSDRTII TIAHRINTII DSDRIVVLDK
GRVAEFDTPA ELIKGGGQFY ELAKEAGLLD SDGGIASSQ
//
