ID A0A0A2JYB5_PENEN Unreviewed; 402 AA.
AC A0A0A2JYB5;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Winged helix-turn-helix transcription repressor DNA-binding {ECO:0000313|EMBL:KGO59811.1};
GN ORFNames=PEX2_053890 {ECO:0000313|EMBL:KGO59811.1};
OS Penicillium expansum (Blue mold rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=27334 {ECO:0000313|EMBL:KGO59811.1, ECO:0000313|Proteomes:UP000030143};
RN [1] {ECO:0000313|EMBL:KGO59811.1, ECO:0000313|Proteomes:UP000030143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-8 {ECO:0000313|EMBL:KGO59811.1,
RC ECO:0000313|Proteomes:UP000030143};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO59811.1}.
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DR EMBL; JQFZ01000089; KGO59811.1; -; Genomic_DNA.
DR RefSeq; XP_016600914.1; XM_016742663.1.
DR AlphaFoldDB; A0A0A2JYB5; -.
DR STRING; 27334.A0A0A2JYB5; -.
DR GeneID; 27678082; -.
DR HOGENOM; CLU_005533_5_0_1; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000030143; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd22958; DD_DPY30_SDC1-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:KGO59811.1};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000030143};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 216..378
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 307
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 402 AA; 45168 MW; 718EC15DED421177 CRC64;
MNIKHLQCLL AEAKALLDSY EATQTDTFRV EAQEKAAQLA RALERPKDTI VKLAFSPTIL
MAVKIAHDMN VFPVLAQATG PVPLAELAAA KPADPLLVER IMRVLVANGF VEEPAPSEYL
PTAVSRQMTQ RPLIGVVEAL FYEFLPSINK APEHLQSINH RNPDDPLSAA LQYTHDMNID
GFTWLCRNPE ALNRFNYCME GQRADRPHWG DWFPVHERLL DHPDMTAEIP LLVDIGAGGG
HDLIGFRKRF PDAPGKLVVE DLLPVIEELR GAQDLEASSI DTVAHDFFAE VQPVRGARAY
YFKHVLHDWS DEKATIIFNN LKPAMRRGFS KIIIEEYILP DQNARLLPCM MDMAVMVFCS
GLERTRQRWS DLLTSVGLRA IKFWVREGDG LGIIEAELAE SV
//
