ID A0A0A2KCX6_PENIT Unreviewed; 434 AA.
AC A0A0A2KCX6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Translation initiation factor eIF2B subunit beta {ECO:0000256|ARBA:ARBA00044122};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit beta {ECO:0000256|ARBA:ARBA00044228};
GN ORFNames=PITC_052860 {ECO:0000313|EMBL:KGO64741.1};
OS Penicillium italicum (Blue mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=40296 {ECO:0000313|EMBL:KGO64741.1, ECO:0000313|Proteomes:UP000030104};
RN [1] {ECO:0000313|EMBL:KGO64741.1, ECO:0000313|Proteomes:UP000030104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI-1 {ECO:0000313|EMBL:KGO64741.1,
RC ECO:0000313|Proteomes:UP000030104};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO64741.1}.
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DR EMBL; JQGA01001564; KGO64741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2KCX6; -.
DR STRING; 40296.A0A0A2KCX6; -.
DR HOGENOM; CLU_016218_4_3_1; -.
DR OMA; SHSCAVA; -.
DR OrthoDB; 169494at2759; -.
DR PhylomeDB; A0A0A2KCX6; -.
DR Proteomes; UP000030104; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45859; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR PANTHER; PTHR45859:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR Pfam; PF01008; IF-2B; 2.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:KGO64741.1};
KW Protein biosynthesis {ECO:0000313|EMBL:KGO64741.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030104}.
FT REGION 115..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 434 AA; 47285 MW; 8F6D518D22DD810C CRC64;
MPSSSLALTP GLGSFLKCLK TNPIDTSIET LISLLKRRQI RHSRSCATAT AYLLRSVISA
CRTADSAKLI ERVQSVGRRL MAAQPREMVV GNIVRRVLGL IRDEAEDDRD AEFALSDIGS
ESQPQTPRAY DDPSLPLDRD SLSFRSEERS SRPPLTSMFS LLSHPEPENS LPSTPGSSSP
NGRLPGHGPS KDVRAEVLEG IGEIIDELGQ VDDQIAAYAL DHIHSNEIIL THTSSTTVQK
FLLKAAAKRK FTVIHAESYP NNHEATHATI SGSAVSDDDN LGLEAFQKPL IEHGITVILI
PDSAVFALMS RVNKVILGTH SVLANGGLVA AAGTRVIARA AKVHQTPVVV VSGVYKLSPV
YPFDFDSLIE YGDPSKVLPY EEGDLVDLVD VQNPIYDYVP AELVDLYITN LGGHAPSYLY
RIVSDHYRKE DISF
//
