ID A0A0A2L5Y2_PENIT Unreviewed; 732 AA.
AC A0A0A2L5Y2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein HRI1 {ECO:0000256|ARBA:ARBA00017063};
GN ORFNames=PITC_080800 {ECO:0000313|EMBL:KGO75394.1};
OS Penicillium italicum (Blue mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=40296 {ECO:0000313|EMBL:KGO75394.1, ECO:0000313|Proteomes:UP000030104};
RN [1] {ECO:0000313|EMBL:KGO75394.1, ECO:0000313|Proteomes:UP000030104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI-1 {ECO:0000313|EMBL:KGO75394.1,
RC ECO:0000313|Proteomes:UP000030104};
RX PubMed=25338147; DOI=10.1094/MPMI-09-14-0261-FI;
RA Ballester A.R., Marcet-Houben M., Levin E., Sela N., Selma-Lazaro C.,
RA Carmona L., Wisniewski M., Droby S., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome, transcriptome, and functional analyses of Penicillium expansum
RT provide new insights into secondary metabolism and pathogenicity.";
RL Mol. Plant Microbe Interact. 28:232-248(2015).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HRI1 family.
CC {ECO:0000256|ARBA:ARBA00005229}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO75394.1}.
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DR EMBL; JQGA01000470; KGO75394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2L5Y2; -.
DR STRING; 40296.A0A0A2L5Y2; -.
DR HOGENOM; CLU_378599_0_0_1; -.
DR OrthoDB; 509202at2759; -.
DR PhylomeDB; A0A0A2L5Y2; -.
DR Proteomes; UP000030104; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd11059; CYP_fungal; 1.
DR CDD; cd11693; HRI1_C_like; 1.
DR CDD; cd11692; HRI1_N_like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR Gene3D; 2.40.128.320; Protein HRI1, N-terminal domain; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR InterPro; IPR031818; Hri1.
DR InterPro; IPR038744; Hri1_N.
DR InterPro; IPR043047; Hri1_N_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF164; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF16815; HRI1; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030104}.
SQ SEQUENCE 732 AA; 82998 MW; 14D25D3FC2B82B3D CRC64;
MLSLWAGAIV LCGYFVISGL LSPLSTIPGP WYTRFTSLWI KYQEFTANRR ESIHRLHKIY
GPVVRLSPNE VSFTSLDAIK EIYASGGSGY DKTEYYDLFR QFKIKTMFSI LLKDEHSKRK
RIFADRYAMT NIMKEKPMAV IHERATTFVS KCVEAGQKSV DVYSLLHCYA LDCVTHFMFS
PGGLRSLNVA EDFEIMHELT YHQSLQKNLL EYYLPSLAPY FPKFLHARSA PKANQYVVDM
TSKTELDSHS LMEKLQRKES NLELMQAAAE CKDHMAAGID TTGDGLCFLM WELSQPLNLC
FQDKLYKEFS AAPADAPLDS YVYLDAVIKE ALRCAPPIPM SLPRYVPAGG REIDGYIVPG
NTIVSCQPYS VHRINESVFP EPDRFNPDRW LVEERAVERN RLFFSFATGG RGCTGKNLAL
VEMKMLLREV YSRYRTTVAS DMTASMKLDD QIISSRPKGQ SYRNLTTTKS NNMASIKPDQ
SSCRFSKRIS FRWLTTPAEE TTDTIVMSVK DWYVDLRIET ATGKIDWAIA GQRIVESQEP
LRVTFSHELD SHNAFETIDC GTFVPLPNGD DLEMGSMPRH DLPGAPDKEY EEVWRELPFR
EGPEGPKKGL SWVLESDDGD LSSGEREVTV QKTFIGRIWG TYLALRQTQT HTRQKTSSGG
LVVKKTGADV SARREEWESG WKEKYLVGEA ASSLPSMVVG FDGEGEGSWR IPGEKVQVQG
KTYIVRAFEE IQ
//
