ID A0A0A2MCY5_9FLAO Unreviewed; 722 AA.
AC A0A0A2MCY5;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=DNA mismatch repair protein MutS {ECO:0000313|EMBL:KGO86130.1};
GN ORFNames=Q765_12495 {ECO:0000313|EMBL:KGO86130.1};
OS Flavobacterium rivuli WB 3.3-2 = DSM 21788.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1121895 {ECO:0000313|EMBL:KGO86130.1, ECO:0000313|Proteomes:UP000030152};
RN [1] {ECO:0000313|EMBL:KGO86130.1, ECO:0000313|Proteomes:UP000030152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WB 3.3-2 {ECO:0000313|EMBL:KGO86130.1,
RC ECO:0000313|Proteomes:UP000030152};
RA Zeng Z., Chen C.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGO86130.1}.
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DR EMBL; JRLX01000013; KGO86130.1; -; Genomic_DNA.
DR RefSeq; WP_020214492.1; NZ_KB899974.1.
DR AlphaFoldDB; A0A0A2MCY5; -.
DR STRING; 1121895.GCA_000378485_03317; -.
DR eggNOG; COG1193; Bacteria.
DR OrthoDB; 9808166at2; -.
DR Proteomes; UP000030152; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48378:SF1; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030152}.
FT DOMAIN 12..316
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 335..520
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT COILED 523..557
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 722 AA; 82901 MW; AD9DB511416E1884 CRC64;
MISITEKTLK DLEFYTVLEA VASACTTEPG REKALLITPL KSKELLMDAL LQTSEYVSSF
DNNNALPNHG FESITNEVKF LAIEDSYLDA GAFRKIALVS DTVNTLVKFL DKFNDYYPTL
NARAQQVEYT KDILKFIDKV VDKYGDIKDD ASPELQNIRR EMNLVKVKIN QSFTMALSQY
NGLGYLDDIK ESVVENRRVL AVSAMYRKKV KGSILGSSKT GSIAYIEPEA TLRFSRELNN
FEYEEKEEIK RILMQLSYAI RPFVPLLYDY QEFLTDIDVV SGKAKYAKRI NGLLPHINDE
RRLYFREAFH PILYVNNRAK NQVTYPQTIE LKPDNRIIVI SGPNAGGKSI TLKTIGLLQL
MLQCGLLIPV HERSETFLFD RIMTDIGDNQ SIENHLSTYS YRLKNMNYFL KKCNDKTLFL
IDEFGTGSDP ELGGALAEIF LEEFYHREAF GIITTHYTNL KILANELPYA TNANMLFDEK
SLEPMYKLIL GQAGSSFTFE VAQKNGIPYG LINRAKKKIE GSKVRFDKTI ATLQKERSKL
EKTSQTLKEE EIRAREEGRK MEGINTRIQQ KLESYQELYD ANQRLIYLGQ KLEDMSEKYY
NNKNKKDLIG EFLKMVEIEN SKRKKVTPKE KKVKEVIQKQ VIAEVEVKVE EIRQEKKEKK
LKEKPVDKPK AILKIGDRVR MVDGKAVGTL DAIEKKKATV NYGIFTSKVD LESLELVEAM
KK
//
