GenomeNet

Database: UniProt
Entry: A0A0A2TPL4_9BACL
LinkDB: A0A0A2TPL4_9BACL
Original site: A0A0A2TPL4_9BACL 
ID   A0A0A2TPL4_9BACL        Unreviewed;       293 AA.
AC   A0A0A2TPL4;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   10-APR-2019, entry version 21.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=P364_0130275 {ECO:0000313|EMBL:KGP78022.1};
OS   Paenibacillus sp. MAEPY2.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Paenibacillus.
OX   NCBI_TaxID=1395587 {ECO:0000313|EMBL:KGP78022.1, ECO:0000313|Proteomes:UP000030061};
RN   [1] {ECO:0000313|EMBL:KGP78022.1, ECO:0000313|Proteomes:UP000030061}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAEPY2 {ECO:0000313|EMBL:KGP78022.1,
RC   ECO:0000313|Proteomes:UP000030061};
RX   PubMed=24526641;
RA   Chua P., Yoo H.S., Gan H.M., Lee S.M.;
RT   "Draft Genome Sequences of Two Cellulolytic Paenibacillus sp. Strains,
RT   MAEPY1 and MAEPY2, from Malaysian Landfill Leachate.";
RL   Genome Announc. 2:0-0(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGP78022.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AWUK01000052; KGP78022.1; -; Genomic_DNA.
DR   RefSeq; WP_024633952.1; NZ_AWUK01000052.1.
DR   STRING; 1395587.P364_0130275; -.
DR   EnsemblBacteria; KGP78022; KGP78022; P364_0130275.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000030061; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030061};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254}.
FT   DOMAIN        2    190       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      206    283       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        183    183       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   293 AA;  32640 MW;  215C91016AFC9069 CRC64;
     MKRIAVLPEG SVSHEAVDFL FNGEPLELLH SKLISDVFRA TDSGKSEYSV IPIENTIEGS
     VSLHMDWLVN EVDIPMQAEW VYPSIQNVIG HGSEFRTESG EYDFGKITKI MSHPVAIPQC
     QNFIRLHSPG ADLEGVNSTA EAVEIVKKNP GKGWVAIGTR LAAQKHGLDI MAERVTDHDN
     NYTRFVLIGY EPVQIPREPD HVKTSLLVTL PEDAPGALHQ VLSAFAWRKL NLTRLESRPT
     KKRLGSYYFY IDVEESADSV LLTAAMAEIE ALNCQVRVLG SYPCYTYPSL KTT
//
DBGET integrated database retrieval system