ID   A0A0A2UYJ1_9BACI        Unreviewed;       673 AA.
AC   A0A0A2UYJ1;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Heparinase {ECO:0000313|EMBL:KGP92994.1};
GN   ORFNames=N780_11705 {ECO:0000313|EMBL:KGP92994.1};
OS   Pontibacillus chungwhensis BH030062.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX   NCBI_TaxID=1385513 {ECO:0000313|EMBL:KGP92994.1, ECO:0000313|Proteomes:UP000030153};
RN   [1] {ECO:0000313|EMBL:KGP92994.1, ECO:0000313|Proteomes:UP000030153}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BH030062 {ECO:0000313|EMBL:KGP92994.1,
RC   ECO:0000313|Proteomes:UP000030153};
RA   Wang Q., Wang G.;
RT   "Genome of Pontibacillus chungwhensis.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGP92994.1}.
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DR   EMBL; AVBG01000001; KGP92994.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0A2UYJ1; -.
DR   STRING; 1385513.N780_11705; -.
DR   eggNOG; COG5360; Bacteria.
DR   Proteomes; UP000030153; Unassembled WGS sequence.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.70; -; 1.
DR   Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR012480; Hepar_II_III.
DR   InterPro; IPR031680; Hepar_II_III_N.
DR   PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR   PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR   Pfam; PF07940; Hepar_II_III; 1.
DR   Pfam; PF16889; Hepar_II_III_N; 1.
DR   SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030153};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          40..303
FT                   /note="Heparin-sulfate lyase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16889"
SQ   SEQUENCE   673 AA;  78832 MW;  0EC4B0C573349B63 CRC64;
     MNKSFFYHTP DQREIIDFCK TAWPEEVREV IHRADLATKQ TFIFTHRWDM ERCEIPVTFD
     NKIDWTYRFK GDFEWTVNLN RSRFMSELGQ AYWLTSDEKY VTSFINLLKD WINQNPLSID
     EILSSKEQHY NVKDTWRKLD SGIRITNWLK GYHCVRESDY WTREDEQLFK EAVHLHGTYL
     KFAFTPHDRQ SNWGFLETNG LFQIAMLFPE FAESKSWLSI AVDRLVNMCE LQIFEDGMHN
     EQSPMYHHEV LHCLFECVWL AKKNEHPLPS ICEDSLKRLF LSSLAFVKPT GSQPMISDSD
     DTDIRDILCR GAVLFKRGDL KHQAYDQLDY ESAWYYGKEG IDEFHKLVAH PPSTTSIHLS
     ESGYSIMRSG WSESSHYCLF DGGHMDIIQA HGHDDFLHLD LNVFGKDLLI DTGRYTYMEG
     EERRYFKESF QHNTTIVDHT SISEFKDSWT WGDIARTTQS FWKTCESFDY AEAGHDGYRN
     LKDPVGVLRK ILFVKPYYWL VIDEFQSNET HHFAQHFHVS ENVSVQTYPD RSVAVCNLNE
     KEGLFIHSIT PAKLTKDKCW ISRNYNEKHA SSKLVFDHKA TGKTRMITGL IPFHSTVTED
     VVIKEIGVRN TFGDYFSNED VTAMEINIGM DTHWVVVSHS GPNSFQFAEH HMTGDVLLVK
     KKGDQLNKWV IKV
//