ID A0A0A2V0H8_9BACI Unreviewed; 405 AA.
AC A0A0A2V0H8;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Nucleoside permease {ECO:0000256|RuleBase:RU362018};
GN ORFNames=N780_01760 {ECO:0000313|EMBL:KGP92296.1};
OS Pontibacillus chungwhensis BH030062.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX NCBI_TaxID=1385513 {ECO:0000313|EMBL:KGP92296.1, ECO:0000313|Proteomes:UP000030153};
RN [1] {ECO:0000313|EMBL:KGP92296.1, ECO:0000313|Proteomes:UP000030153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BH030062 {ECO:0000313|EMBL:KGP92296.1,
RC ECO:0000313|Proteomes:UP000030153};
RA Wang Q., Wang G.;
RT "Genome of Pontibacillus chungwhensis.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033,
CC ECO:0000256|RuleBase:RU362018}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGP92296.1}.
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DR EMBL; AVBG01000003; KGP92296.1; -; Genomic_DNA.
DR RefSeq; WP_036781508.1; NZ_AVBG01000003.1.
DR AlphaFoldDB; A0A0A2V0H8; -.
DR STRING; 1385513.N780_01760; -.
DR eggNOG; COG1972; Bacteria.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000030153; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR018270; C_nuclsd_transpt_met_bac.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR NCBIfam; TIGR00804; nupC; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362018};
KW Reference proteome {ECO:0000313|Proteomes:UP000030153};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362018};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362018}; Transport {ECO:0000256|RuleBase:RU362018}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 253..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 291..307
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 381..404
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT DOMAIN 10..82
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 93..188
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 196..401
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 405 AA; 43045 MW; AADCE1CB0BC76A4E CRC64;
MSNILWGLGG MLTIFLIAIL FSTNRKAINW RTVAGGLAIQ ITFAFLVFVT TWGQNILQYM
SQSVNNLIGY TTEGIEFLYG PLINHENMGM MFAFQVLPTI IFFSSLIAVL YHLGIMQKII
MLIGGLLSKV LGTTKVESIN AAGNIFVGQT EAPLLIRPFI SRITKSELFA VMTGGFTSIA
GSTLVGYTLL GIEVEYLLAA SFMAAPAALV LAKLFVPEVE PHHEVIEDVA PEESDTTNVF
DAIAGGAVTG LKLAVNIGAI LLSFIALLAL LNGIIGWVGN LFDVAITLEK LLGYLLAPLA
FVIGVPWDEA VRSASFIGQK IVTNEFVAFS SLGEVKGELS EKAEIVTTFA LTGFGSLSGI
GVQIGALGGM APDRRKDVAN LGLRAVIAAT LANLLSASIA GMFLF
//
