ID A0A0A2VDB2_BEABA Unreviewed; 1071 AA.
AC A0A0A2VDB2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=sn-1-specific diacylglycerol lipase {ECO:0000256|ARBA:ARBA00026104};
DE EC=3.1.1.116 {ECO:0000256|ARBA:ARBA00026104};
GN ORFNames=BBAD15_g8857 {ECO:0000313|EMBL:KGQ05876.1};
OS Beauveria bassiana D1-5.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=1245745 {ECO:0000313|EMBL:KGQ05876.1, ECO:0000313|Proteomes:UP000030106};
RN [1] {ECO:0000313|EMBL:KGQ05876.1, ECO:0000313|Proteomes:UP000030106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D1-5 {ECO:0000313|EMBL:KGQ05876.1,
RC ECO:0000313|Proteomes:UP000030106};
RA Li Q., Wang L., Zhang Z., Wang Q., Ren J., Wang M., Xu W., Wang J., Lu Y.,
RA Du Q., Sun Z.;
RT "Genome sequencing and analysis of entomopathogenic fungi Beauveria
RT bassiana D1-5.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty
CC acid + H(+); Xref=Rhea:RHEA:33275, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17389, ChEBI:CHEBI:17815,
CC ChEBI:CHEBI:28868; EC=3.1.1.116;
CC Evidence={ECO:0000256|ARBA:ARBA00024531};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:33276;
CC Evidence={ECO:0000256|ARBA:ARBA00024531};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ05876.1}.
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DR EMBL; ANFO01000907; KGQ05876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2VDB2; -.
DR STRING; 1245745.A0A0A2VDB2; -.
DR eggNOG; KOG2088; Eukaryota.
DR HOGENOM; CLU_001871_0_0_1; -.
DR Proteomes; UP000030106; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd00519; Lipase_3; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002921; Fungal_lipase-like.
DR PANTHER; PTHR45792; DIACYLGLYCEROL LIPASE HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45792:SF7; PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02710)-RELATED; 1.
DR Pfam; PF01764; Lipase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000030106};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 752..918
FT /note="Fungal lipase-like"
FT /evidence="ECO:0000259|Pfam:PF01764"
FT REGION 339..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 587..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1071 AA; 116494 MW; BF670A9EC21F8264 CRC64;
MASGKTPKHN PGPTLLPGPI ASTVSLATRS TSLAIRIGSV VGGYGLNAAR FTTLSSLELA
RGLVEVVLTR AGKDTLDHAK SSLAAADAEN VLERSLEGLH YAVIQVAFWT SASFRLTGTT
LSLASNTSQL LLSSLDKLLG STDSSRAVAS IITLMRREFR NPVTGFQGER VGVIDLTLAL
SALAYLQQAC RKLPEEEARR NAFEEVIWDV VVLNDGDRVE FDDKIALQRG YAPAFNHEAS
RRGSQDEEAL AQLESHITQS LPPEAKVTIS SYVTTVQTIT VEVEGCLPVL PTPPGAEIIE
TTAPVSRSKR LSYPGHDNDG PYRVVYKIER DKFRVKNLQG GDDIETGSVL GEIESDKESP
TPMQYNPATG TFLPVPAPSP PPKDVDDHES KSPPASPSSE ENDNIPKSIP TRKPEPTANQ
KRQRQPAAAV SNKANAQNTI RISQKKKTDG IGRAVDKKPG LKQVLKEGSQ SISNMWNKDG
IENGSRARQG NTASSRAESS QKVTALHNRP TKASQERSIA NRRSIATPEP LNRSSSRTSY
LSLSDRRHSI AQSSYNAVTG GMKPPSPTLT KDSPFLQDST FRSRRGSLLG TTVPASPMRG
HRRSGSHAPS IYSLATNDSQ TSLVLSSYYK KSTYSAADAL HTLRQEGFVD GTFPEGHLLP
NITRYMRFSS ACYGSHFLKF LGISNNMPKM TSWDGIHQDV RHFAHHTESN TGNILLASFV
DPQGGSDSTG ATGTGVPLVH YISLDHEAKA VVLACRGTLG FEDVMADMTC DYDDLVWKKR
SYKVHKGVHA SARRLLYGGD GRVLVTLKEA LAEFPDYGLV LCGHSLGGGV TALLGVMLAE
ANPNGPGFVT APEAAFKKML TDERSNSNVH NEVFIPAGRR IHVYAYGSPG VMSPKLRRIT
RGLITTVVHG DDLVPHLSLG ILHDFQALTL AFKDKENATK ADMRKRMWAA IQGNLSYAWH
GGSESRAVPG NDEHKWMLPA LAALRENFTC ERLVPPGEVF VIESYPALRR EAFLLNGEGL
LGRPATRVIL KYVRDVETRF LEPRFGTSML TDHSPANYEN ALNKMRLGVV D
//
