ID A0A0A2VTW6_BEABA Unreviewed; 949 AA.
AC A0A0A2VTW6;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cytochrome c-type biogenesis protein CcmF {ECO:0000313|EMBL:KGQ11366.1};
GN ORFNames=BBAD15_g2903 {ECO:0000313|EMBL:KGQ11366.1};
OS Beauveria bassiana D1-5.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=1245745 {ECO:0000313|EMBL:KGQ11366.1, ECO:0000313|Proteomes:UP000030106};
RN [1] {ECO:0000313|EMBL:KGQ11366.1, ECO:0000313|Proteomes:UP000030106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D1-5 {ECO:0000313|EMBL:KGQ11366.1,
RC ECO:0000313|Proteomes:UP000030106};
RA Li Q., Wang L., Zhang Z., Wang Q., Ren J., Wang M., Xu W., Wang J., Lu Y.,
RA Du Q., Sun Z.;
RT "Genome sequencing and analysis of entomopathogenic fungi Beauveria
RT bassiana D1-5.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase. {ECO:0000256|ARBA:ARBA00037230}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|ARBA:ARBA00009186}.
CC -!- SIMILARITY: Belongs to the CcmH/CycL/Ccl2/NrfF family.
CC {ECO:0000256|ARBA:ARBA00010342}.
CC -!- SIMILARITY: Belongs to the peroxiredoxin family. Prx5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010505}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. DsbE subfamily.
CC {ECO:0000256|ARBA:ARBA00007758}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ11366.1}.
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DR EMBL; ANFO01000221; KGQ11366.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A2VTW6; -.
DR STRING; 1245745.A0A0A2VTW6; -.
DR HOGENOM; CLU_310130_0_0_1; -.
DR Proteomes; UP000030106; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW.
DR GO; GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR CDD; cd16378; CcmH_N; 1.
DR Gene3D; 1.10.8.640; Cytochrome C biogenesis protein; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR005616; CcmH/CycL/Ccl2/NrfF.
DR InterPro; IPR038297; CcmH/CycL/NrfF/Ccl2_sf.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR InterPro; IPR004799; Periplasmic_diS_OxRdtase_DsbE.
DR InterPro; IPR013740; Redoxin.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00385; dsbE; 1.
DR NCBIfam; TIGR00353; nrfE; 1.
DR PANTHER; PTHR43653; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43653:SF1; CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF03918; CcmH; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR Pfam; PF08534; Redoxin; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030106};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 508..631
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 949 AA; 105422 MW; FF03089EF781B31D CRC64;
MGGARRVVDA LGADDERLDV CRLPHRAQYA NRRSCPRAGG RDLNPLLQDI GLILHPPLLY
MGYVGFSVAF AFSIAALLGG RLDSAWARWT RPWTLAAWAF LTVGIVLGSA WAYYELGWGG
WWFWDPVENA SFMPWLAGTA LIHSLSVTEK RGSFKAWTVL LAISAFSLCL LGTFLVRSGV
LVSVHSFASD PARGMFILAF LVVVIGGSLL LYAVKGSKVR SRVSNDLWSR ESFLLGNNVL
LIAAMLVVLL GTLLPLVHKQ LGLGSISIGE PFFNTMFTAL MAPFALMLGI GPLVRWRRDE
PGKLRKHLLA AVAITLILSL LLPWLMQDRV EAMTVVGLLM AVWVFVLALM EVYQRATHRH
GFWDGLRKIP ASHWGMVSAH LGLAVTVVGI AFSQSYSVER DVRMKSGDSI DIHQYHFVFR
EVRDITGPNY RGGVGVIDVT RHGKPEATLH AEKRFYNSNR AMMTEAAIDG GFTRDLYAAL
GEELADGSWA VRLYYKPFGE APTDLESALI GKPVPVFRLE SLDEPGKEWG REVLADGKPL
LLNVWATWCP TCRAEHKFLN GLAAQGVRVV GMNYKDDRHK AINWLRDLGN PYMLSLFDGN
GMLFSVHAAA TIDTFTFKDE AQEQQFRQLT EALRCPKCQN NSIADSNAMI ASDMKLKVYE
LMQQGKSKQQ IVDYMVERYG HFVTYEPPLT PATVILWVLP ALFILGGATV IVLRSRRRQK
ISLSEENPTL SRGISPGKIS LWVFLPGAVL LVAVSVGSYL KTSGLAQVHA WRQATAETPA
LLKRVLDPQA APLTMEEMAR LGLGLRTRLQ QQPDNLEGWM MLGRIGMVLN NATTATQAFA
HAWKLAPTNS EAKLGYAEIL TRSADEQDNQ LGGLLLREML KDDHTNIRVL SLLAFNAFER
QNYREAIGAW DMMLRILPAN DQRRAVIERS IDRARAQLEP GTTESADKQ
//
