ID A0A0A2W4W9_BEABA Unreviewed; 1845 AA.
AC A0A0A2W4W9;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=PTS system N-acetylmuramic acid-specific EIIBC component {ECO:0000313|EMBL:KGQ13495.1};
GN ORFNames=BBAD15_g677 {ECO:0000313|EMBL:KGQ13495.1};
OS Beauveria bassiana D1-5.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria.
OX NCBI_TaxID=1245745 {ECO:0000313|EMBL:KGQ13495.1, ECO:0000313|Proteomes:UP000030106};
RN [1] {ECO:0000313|EMBL:KGQ13495.1, ECO:0000313|Proteomes:UP000030106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D1-5 {ECO:0000313|EMBL:KGQ13495.1,
RC ECO:0000313|Proteomes:UP000030106};
RA Li Q., Wang L., Zhang Z., Wang Q., Ren J., Wang M., Xu W., Wang J., Lu Y.,
RA Du Q., Sun Z.;
RT "Genome sequencing and analysis of entomopathogenic fungi Beauveria
RT bassiana D1-5.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ13495.1}.
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DR EMBL; ANFO01000039; KGQ13495.1; -; Genomic_DNA.
DR STRING; 1245745.A0A0A2W4W9; -.
DR HOGENOM; CLU_237026_0_0_1; -.
DR Proteomes; UP000030106; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008294; F:calcium- and calmodulin-responsive adenylate cyclase activity; IEA:InterPro.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0016835; F:carbon-oxygen lyase activity; IEA:InterPro.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0046348; P:amino sugar catabolic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd05007; SIS_Etherase; 1.
DR Gene3D; 1.10.8.1080; -; 1.
DR Gene3D; 2.30.29.80; -; 1.
DR Gene3D; 3.90.1760.10; Anthrax toxin, edema factor, central domain; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR HAMAP; MF_00068; MurQ; 1.
DR InterPro; IPR035099; Anthrax_toxin_C-terminal.
DR InterPro; IPR005165; Anthrax_toxin_edema_cen.
DR InterPro; IPR037017; Anthrax_toxin_edema_cen_sf.
DR InterPro; IPR010879; DUF1508.
DR InterPro; IPR005488; Etherase_MurQ.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR005486; Glucokinase_regulatory_CS.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036913; YegP-like_sf.
DR NCBIfam; TIGR00274; N-acetylmuramic acid 6-phosphate etherase; 1.
DR PANTHER; PTHR30175; PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30175:SF3; PTS SYSTEM N-ACETYLMURAMIC ACID-SPECIFIC EIIBC COMPONENT; 1.
DR Pfam; PF03497; Anthrax_toxA; 1.
DR Pfam; PF07411; DUF1508; 2.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF81298; Adenylylcyclase toxin (the edema factor); 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR SUPFAM; SSF160113; YegP-like; 2.
DR PROSITE; PS01272; GCKR; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000030106};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 660..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 785..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 815..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 862..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 902..921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 928..949
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 955..981
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 993..1014
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1483..1511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1523..1548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1555..1576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1596..1613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1625..1649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1669..1694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1706..1726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1738..1758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1765..1791
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1811..1837
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1153..1316
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 1485..1845
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT REGION 140..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1845 AA; 195590 MW; 7B4D36A48EE17867 CRC64;
MSGWFELSKS SDGQFKFVLK AGNGEVVLTS ELYKTRASAD NGIASVRTNS PLDERYDKKV
ASNGKFYFNL KAGNHQVIGT SQMYATEQSR DKGIASGRRG NPRAFTWGMF SRDAAQAAFS
RPQPQWLVVY RREPGRKMKV GSTPAAYRPA EPHLSAASQP PGTDLQQLVS HLKDKTGIVP
AHLIPLQRVA SEHNCIIGVR PVDKLATALI EAGHPTKGFH IKGKSASWGP QAGFICVEQR
FSKLENASPE RIAKFNLQTQ ACIAEGHAAA VPLDVSQSRL HDLFAQGLID KLSPENAGVL
APHAEARPFT ADYDLMVIAP HVSELGPEDN LQVPDVSHQV FRQRLENYRT LPEHQALRGD
YDNPASFYRK SDEEIGNASE RARRMIGVLN QALVGEGEKV VHHATDSANP VTDPESNYPA
TRSCGAGAAG QERGLPRPAE SALGKGGSWR AQRQVYCREV NAGGGTAHKA GAAALSFCLQ
TCGHPFRVAG IKATDPVAFS TQIFDGFDGK NAVCSPAVGD NFSVFGQFGE ARLQLFEWNI
QGPGKMAIAK FVLWPDPLAG ILVIGSNAAN SLIVVFGKTA KAGNHASDRA ISQAIDDVLT
VAPGGHIVAF SKVLQVLRGA GRRHTRQPGQ HFNGQFSSGE MLQNFNPRAI AQQPRQFAEV
LLLVGAQAIF QTVSVLVMTI GGLAGGQLTP SPGLATAPIA AMFLGTALTT FPASLWMARV
GRKTGFMTGA AAGIAGGVIA GLGIMSGSFL LLCAGTLLVG VYQSFAQFYR FAASEVANDT
FRPKAISLVM TGGIVAALAG PLLARFGSDL MTPRYLGSFM ILAGISFVAV LLLARLSVPA
SREAVANHAP ARPWRAVISQ PAYLTALFSA ATGYGIMILA MTATPLAMSH HHHTLAQTSS
VIQLHVLAMF LPSFITGKLI ARFGSIRVML TGVVLFGCDI LLALTGTGFT SFASALIFVG
LGWNFLYIGG TALLTTTFSA AEKGVAQAVN DMTIFVVGLS CYLSAGALLE WLGWEKLNEL
LLPWLALSAI VLNFIRMRFV ISLNGPGGPL FVLALQNVCV IQAHRQLSVI RLGAHVVQPG
GVDPHQASET HITDVPMKIN LTQLVTEGRN PASAEIDTLP TLEMLKVINN EDKQVPLAVE
ATLPQVAQVV DKVVAAFAQG GRLIYSGAGT SGRLGILDAS ECPPTFGTPR EQVVGLIAGG
HPAILQAVEN AEDNREMGEQ DLRNLNFSAR DVLVGIAASG RTPYVLGAMA YAKSVGATVA
AISCNPGSEM SLAADIAIEP VVGPEIVTGS SRMKAGTAQK LILNMITTGS MIRSGKVYGN
LMVDVEATNA KLIQRQVNIV VAATECSPEQ AEAALSACRR HCKTAIFMLL SGLSAEEASC
LLAKKHGFIR EALRGLTLKN RDLVQHDDLK KIPGVMGVVN GDDQLQIILG PGKAQTASEL
MNSLLKQGGQ SEPEKGDSAD LAALASQNKQ QMKAKQNSAV HNFLTKFATI FTPLIPGFIA
AGLLLGIATL LQQTLVVEGT TPAAWLTQLI AYLKVFSVGL FTFLSILIGF NTQKAFGGTG
VNGAIIASLF ILRYVPEGKV GYYAGMDTFF GLAIDPRGNI IGVLLACMLG AWIERQVRRM
IPDNLDMILT STITLLITGA ITFVAIMPIG GELFKGMSWL FMHLNGNPFG TAILAGLFLI
AVVFGIHQGF VPVYFALMDA QGFNSLFPIL AMAGAGQVGA ALALFARSPK NSALRTQIKG
AIIPGLLGIG EPLIYGVTLP RLKPFITACI GGGVGGFFIG LVAWMGLPVG LNTVFGPSGL
VSIPLMTSHQ GIFAGMAVYV AGIVIAYIAG FIMTWCFGSK NVDLS
//
