ID A0A0A2WXR1_9GAMM Unreviewed; 397 AA.
AC A0A0A2WXR1;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:KGQ17794.1};
GN ORFNames=LF41_2001 {ECO:0000313|EMBL:KGQ17794.1};
OS Lysobacter dokdonensis DS-58.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1300345 {ECO:0000313|EMBL:KGQ17794.1, ECO:0000313|Proteomes:UP000030518};
RN [1] {ECO:0000313|EMBL:KGQ17794.1, ECO:0000313|Proteomes:UP000030518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-58 {ECO:0000313|EMBL:KGQ17794.1,
RC ECO:0000313|Proteomes:UP000030518};
RA Kim J.F., Kwak M.-J.;
RT "Genome sequences of Lysobacter dokdonensis DS-58.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ17794.1}.
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DR EMBL; JRKJ01000025; KGQ17794.1; -; Genomic_DNA.
DR RefSeq; WP_036171960.1; NZ_JRKJ01000025.1.
DR AlphaFoldDB; A0A0A2WXR1; -.
DR STRING; 1300345.LF41_2001; -.
DR PATRIC; fig|1300345.3.peg.3048; -.
DR eggNOG; COG0626; Bacteria.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000030518; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR011821; O_succ_thio_ly.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR02080; O_succ_thio_ly; 1.
DR PANTHER; PTHR11808:SF75; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000030518}.
FT MOD_RES 199
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 397 AA; 42192 MW; CF1CDAE071ECEAC4 CRC64;
MSAFHPCTAA VRAGIDRDEA YGAVVPPIVL SSNFSFAAFD EKRRYDYTRS GNPTRDLLAD
ALAELEGGAG AVITATGMAA ITLVLNAYLK PGDVLVATHD AYGGSWRLFD ALARKGHFEL
VLADLADPRA LTAALERKPA LVWIETPSNP LLRITDLRFT IEAAHAAGAR TVVDNTFLSP
ALQQPIAFDA DLVVHSTTKY INGHSDVVGG AVVARTAEDH QTLTWWANAL GITGAPFDSF
LTLRGLRTLG ARIRVHQENA RAIAALIDDH PVVRAVHYPG LAHHPGHALA KRQQSGFGAM
LSLELDGGID AVRAFLDGLR CFTLAESLGG VESLVAHPAT MTHAAMSPQA RAAAGIGDGL
LRLSVGIEHA DDLLADIADA LERAHAVVRD QRREVAT
//
