ID A0A0A2X9I3_THEFI Unreviewed; 626 AA.
AC A0A0A2X9I3;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=THFILI_10265 {ECO:0000313|EMBL:KGQ21864.1};
OS Thermus filiformis.
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=276 {ECO:0000313|EMBL:KGQ21864.1, ECO:0000313|Proteomes:UP000030364};
RN [1] {ECO:0000313|EMBL:KGQ21864.1, ECO:0000313|Proteomes:UP000030364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43280 {ECO:0000313|EMBL:KGQ21864.1,
RC ECO:0000313|Proteomes:UP000030364};
RA Mandelli F., Ramires B.O., Paixao D.A., Camilo C.M., Polikarpov I.,
RA Couger M.B., Prade R., Riano-Pachon D.M., Squina F.M.;
RT "Draft Genome Sequence of the thermophile Thermus filiformis ATCC43280
RT producer of carotenoid-(di)glucoside-branched fatty acids (di)esters.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ21864.1}.
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DR EMBL; JPSL02000040; KGQ21864.1; -; Genomic_DNA.
DR RefSeq; WP_038064406.1; NZ_JPSL02000040.1.
DR AlphaFoldDB; A0A0A2X9I3; -.
DR STRING; 276.THFILI_10265; -.
DR PATRIC; fig|276.5.peg.1329; -.
DR OrthoDB; 23610at2; -.
DR Proteomes; UP000030364; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KGQ21864.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 28..80
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 86..471
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 526..603
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 626 AA; 69976 MW; 607BF4D0CFA7B1D7 CRC64;
MVEKLLKGEE RLWAPENVRQ AANLKDFAEE YQRSLEDPEG FWGAWARRFH WEKPFERVLE
WDLPEHRWFL GGLTNAVYNA LDRNVARGLR NKLALLYLSE DGKEEKLTYG ELLDRVRRFA
TALRALGVGK GDRVVIYMPL TLEGVIAMLA TAYLGAIHSV VYAGLGVSAL RERILDAGAK
LLIAGDVTYR RGKAVDLRSI AEAAIEDLPL QVVWFQRAYQ AELPPNHHDF QELLWSHRPE
AEAEWVEAEH PLFILYTSGS TGKPKGVVHV HGGYMVGTTY HLRTFFDAKD EDVFWATSDI
GWIVGHSYIV YAPLLEGLTS VLREGAPDHP DPGAFWKAVE RYRVNVMFTA PTAVRMFMKY
GPEWPRKYDL SSLRLVAVAG EPLNPEALRW AYAHLADEGR RGFVADNWWQ TELGGPTLGT
PLVLPAKPGY AGVALPGVEA AVYSEEGREV PRGQGGLLVL KRPFPHMMRT VWGNHERYLQ
YWRELPALVY VAGDVASQDE EGYFSVLGRA DDVLNVAGHR IGTADVESAL VSHPAVAEAA
VIGVPDPLKG EAIKAFVVLR SGHAPSEELK ENIVQHVRRE LGPIATPQEV VFLDKLPKTR
SGKILRRLLK AQELGKDPGD LSTLEE
//
