ID A0A0A3BD00_9PAST Unreviewed; 757 AA.
AC A0A0A3BD00;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=CRISPR-associated protein Cas3 {ECO:0000313|EMBL:KGQ71414.1};
GN ORFNames=OA57_01070 {ECO:0000313|EMBL:KGQ71414.1};
OS Chelonobacter oris.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Chelonobacter.
OX NCBI_TaxID=505317 {ECO:0000313|EMBL:KGQ71414.1, ECO:0000313|Proteomes:UP000030380};
RN [1] {ECO:0000313|EMBL:KGQ71414.1, ECO:0000313|Proteomes:UP000030380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1662 {ECO:0000313|EMBL:KGQ71414.1,
RC ECO:0000313|Proteomes:UP000030380};
RA Kudirkiene E., Hansen M.J., Bojesen A.M.;
RT "Draft genome sequence of Chelonobacter oris 1662T, associated with
RT respiratory disease in Hermann's Tortoises.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the N-terminal section; belongs to the CRISPR-associated
CC nuclease Cas3-HD family. {ECO:0000256|ARBA:ARBA00006847}.
CC -!- SIMILARITY: In the central section; belongs to the CRISPR-associated
CC helicase Cas3 family. {ECO:0000256|ARBA:ARBA00009046}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGQ71414.1}.
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DR EMBL; JSUM01000002; KGQ71414.1; -; Genomic_DNA.
DR RefSeq; WP_034612308.1; NZ_JSUM01000002.1.
DR AlphaFoldDB; A0A0A3BD00; -.
DR STRING; 505317.OA57_01070; -.
DR OrthoDB; 9810236at2; -.
DR Proteomes; UP000030380; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd09641; Cas3''_I; 1.
DR CDD; cd17930; DEXHc_cas3; 1.
DR Gene3D; 1.10.3210.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006483; CRISPR-assoc_Cas3_HD.
DR InterPro; IPR038257; CRISPR-assoc_Cas3_HD_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR006474; Helicase_Cas3_CRISPR-ass_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01587; cas3_core; 1.
DR NCBIfam; TIGR01596; cas3_HD; 1.
DR PANTHER; PTHR47957; ATP-DEPENDENT HELICASE HRQ1; 1.
DR PANTHER; PTHR47957:SF3; ATP-DEPENDENT HELICASE HRQ1; 1.
DR Pfam; PF00270; DEAD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51643; HD_CAS3; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030380}.
FT DOMAIN 16..180
FT /note="HD Cas3-type"
FT /evidence="ECO:0000259|PROSITE:PS51643"
FT DOMAIN 249..436
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 757 AA; 84996 MW; C65254B11837794D CRC64;
MRKPIKYYAH SGKREDHCDW QTLRSHARNV GELAAGFAVF FGAQEMARYT GQLHDVGKYA
PEFNARLHGG KKVDHATAGA KIAFEKYPYI GKLMAFCIAG HHAGLANGDG EGDNRRTLKQ
RLDLQFNQHI PQLDKVWQQE IILPENLPEP NLKADQHQPL FSFAFFTRML YSCLVDADFL
DTEAFYAKLE NKPVLRGDSP DLNALQPQFN QFITSFRRRI ATAPNNTPEQ QRNAALNRLR
SDILDHAVAQ AEQPKGLFTL TVPTGGGKTF TSMAFALEHA KQHGMRRVIY VIPFTSIIEQ
NAAEFRKAFG DLGESAVLEH HSSFDDAKLQ DEHSKDKLRL ASENWDKPIV VTTAVQFFES
LFADRSSRCR KLHNITGSVI ILDEAQMLPL HLLLPIMQAI KELAQNYHCS VVMCTATQPA
VQSEHGFYRG FDNVRELAPN PTALFAQLRR TTVQHIGLQT DVDLQAKLAE HPQILIIVNN
RRHARSLYDN AKSLEGVFHL TTLMCAKHRS QTLDAIRCRL KSGKPCRVIA TSLIEAGVDV
DFPLVMRAEA GLDSIAQAAG RCNRESKRPS ESSFVWVFQP EAEWKAPAEL GLLAGAMRGV
VRQYTDDLLS TAAISAYFKE VYTQKGSELD HKKILADHQD AGQSMDFPFQ TIAPKFRMIE
AHMQPLIIPF DNEAEALINR LHHADQIGGI LRKLQPYTVQ IPENALTALY KAGQIEAVNE
PKFGKQFYSL IGLDLYDEVA GLSWDNPDFI ASEQSVF
//
