ID A0A0A3W5A3_9GAMM Unreviewed; 969 AA.
AC A0A0A3W5A3;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Sarcosine oxidase, subunit alpha {ECO:0000313|EMBL:KGT48510.1};
DE EC=1.5.3.1 {ECO:0000313|EMBL:KGT48510.1};
GN ORFNames=GW12_04510 {ECO:0000313|EMBL:KGT48510.1};
OS Acinetobacter sp. HR7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1509403 {ECO:0000313|EMBL:KGT48510.1, ECO:0000313|Proteomes:UP000032870};
RN [1] {ECO:0000313|EMBL:KGT48510.1, ECO:0000313|Proteomes:UP000032870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR7 {ECO:0000313|EMBL:KGT48510.1,
RC ECO:0000313|Proteomes:UP000032870};
RA Ahn S., Kim B.-C.;
RT "Genome sequencing of Acinetobacter sp. strain HR7.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGT48510.1}.
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DR EMBL; JPQO01000032; KGT48510.1; -; Genomic_DNA.
DR RefSeq; WP_034582897.1; NZ_JPQO01000032.1.
DR AlphaFoldDB; A0A0A3W5A3; -.
DR STRING; 1509403.GW12_04510; -.
DR PATRIC; fig|1509403.3.peg.446; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000032870; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KGT48510.1}.
FT DOMAIN 170..423
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 499..583
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 594..857
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 881..961
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 969 AA; 107600 MW; D73AA1FBA2FDBB3F CRC64;
MTKTGLDRLP APYGLLIDRD HQVQFEFDQQ RFSGFAGDSI ASALIASGRW IMSRSFKYHR
PRAPLTMAGQ DANTLIQLPQ EPNVLADCTD IQTITTSSGQ NYSGSLLKDS DAFLGKFSKF
MPVGFYYRSF YKPKGVWKLW EPMIRKKAGL GVLDLNFEPE YYDKAYLFTD VAVIGAGPAG
LKAAITAADA GLKVLLIEQE KVLGGSLNYA RFDIAGQRAN QLRDELINVA EQHANITVLK
EAVCNAWFTD HYLPVIQGKR MYKVRAKQCI VASGSFDQPV VFRNNDLPGV ILTSAVQRLI
KLYAVKPGQK VVILTGNDDG YFAALDLLEA GIAVQALVDM RAGAANAALQ HAVSTKVQCY
FRSTVYEAQH DRAMQHLTGV EIRQITAEGQ VSKDSIHLEC DVLAMSSGYM PVYQLLCQAG
AKLSYDDRRA QFSITGLPKG LHITGSIHGV HAIENVLKDA EHTAQNVIRS VQEKSQFAEE
LSFIESPVNF PWPMFEHPKG KEFVDFDEDL QIRDIINATK SGYRDVQLVK RFSTVGMGPS
QGRHSALPTA RLVAKYTDRS VSETGVTTAR PPFTAEKLAH IAGRGFDPYR QTPMHQRHLE
LGAKMMPAGN WQRPAFYGPA EQRLKNIERE ALNVRQNVGI IDVSTLGGLE IRGADSAEFL
NRLYTFAFAK LPVGKTRYAV MAAEDGVVID DGVAGRISEQ HFYVTATTSG VDRIYQQMLK
WNAQWRLNVD IANVTTAFAA VNVAGPNSRA LMQKVCTDVD FSNEAFPYLG LRLGTIQGIP
VRLLRVGFVG ELGYEIHYPA RYGEFVWDLL MEAGKAWNMQ PFGVETQRLL RLEKGHIIIS
QDTDGMTHPK ECDLSWAVAK SKPWFVGKRS IEILASQPLK RKLVSFVLDK NKTQPLEGHI
VLEGENISGN ITSCEYSPSL DKIIGMAYVG IHQSVEGQTF PIRVEKGEIV QATVVKAPFY
DPENKRQEV
//
