ID A0A0A3ZB37_9GAMM Unreviewed; 714 AA.
AC A0A0A3ZB37;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=ABC transporter {ECO:0000313|EMBL:KGT94984.1};
GN ORFNames=NG99_04885 {ECO:0000313|EMBL:KGT94984.1};
OS Erwinia typographi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=371042 {ECO:0000313|EMBL:KGT94984.1, ECO:0000313|Proteomes:UP000030351};
RN [1] {ECO:0000313|EMBL:KGT94984.1, ECO:0000313|Proteomes:UP000030351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M043b {ECO:0000313|EMBL:KGT94984.1,
RC ECO:0000313|Proteomes:UP000030351};
RA Chan K.-G., Tan W.-S.;
RT "Genome sequence of Erwinia typographi M043b.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + xenobioticSide 1 = ADP + phosphate +
CC xenobioticSide 2.; EC=7.6.2.2;
CC Evidence={ECO:0000256|ARBA:ARBA00034018};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Drug exporter-2
CC (TC 3.A.1.117) family. {ECO:0000256|ARBA:ARBA00006526}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGT94984.1}.
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DR EMBL; JRUQ01000019; KGT94984.1; -; Genomic_DNA.
DR RefSeq; WP_034888993.1; NZ_JRUQ01000019.1.
DR AlphaFoldDB; A0A0A3ZB37; -.
DR STRING; 371042.NG99_04885; -.
DR eggNOG; COG2274; Bacteria.
DR OrthoDB; 6828292at2; -.
DR Proteomes; UP000030351; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008559; F:ABC-type xenobiotic transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd18567; ABC_6TM_CvaB_RaxB_like; 1.
DR CDD; cd02419; Peptidase_C39C; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR033838; CvaB_peptidase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF606; COLICIN V SECRETION-PROCESSING ATP-BINDING PROTEIN; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 159..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..139
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 173..452
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 490..712
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 714 AA; 79244 MW; 5A7A71D834A3AB52 CRC64;
MSFINSLTFG WGRRLPMMQQ TQAAECGLAC VGMVANYYGH SIDLISLRRR FSTSLKGATL
ADVMQMAHRL GMGGRALRLE VEELEKLRRP CILHWDLNHF VVLKKVHRNK ITIHDPARGI
RDIPMDEVSR CFTGVALELV PSASFKPVEE KQSISMMSLV GSVIGIRSVF VQILILSVAM
ELFGILSPFY MQWVMDQVLV SADYDLLSLL GIGFIIVVIL QNAISTLRAW VTTWFSSLLG
VQWTTNVFTK LLGLPMSYFE ERHVGDIVSR FGSISTIQST LTSRFISTLL DGVMAFATLS
MLFIYNSALT WLVIGLFVTY ALIRLVSYRP FRQANEDQIV TAARAQSQLL ETIRGAQAVK
LNNKQETRMV AYANALVETT NKGIVIQRLS IGFSTLQGVI SGVGRVVLIW LAAKQVLDGN
FSVGMLVAFI SFSDQFIGRA SGLIDALIEF RMLRLYGERL ADIVLTDAEE DMEASVAEPA
RTASGAGPAM TVKGLKFRYS ETEPWVLDNC SFILKPGESV AIVGPSGQGK TTLAKLLLGL
LKPQEGTIEV DGIDIRQQGM RSHRERIGCV MQDDILFAGS IADNISFFDS KCDQQRIEQA
ARLAQIHDDI MVMPMGYQSL VGDMGSSLSG GQNQRVLLAR ALYRQPDILV LDEASSHLDV
ERERLINQAI QLMPITRVII AHRPETIRSA DRIICLANGK AFELDYDTLI NVRQ
//
