ID A0A0A4AD04_9GAMM Unreviewed; 281 AA.
AC A0A0A4AD04;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=23S rRNA methyltransferase {ECO:0000313|EMBL:KGT95733.1};
GN ORFNames=NG99_02260 {ECO:0000313|EMBL:KGT95733.1};
OS Erwinia typographi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=371042 {ECO:0000313|EMBL:KGT95733.1, ECO:0000313|Proteomes:UP000030351};
RN [1] {ECO:0000313|EMBL:KGT95733.1, ECO:0000313|Proteomes:UP000030351}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M043b {ECO:0000313|EMBL:KGT95733.1,
RC ECO:0000313|Proteomes:UP000030351};
RA Chan K.-G., Tan W.-S.;
RT "Genome sequence of Erwinia typographi M043b.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGT95733.1}.
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DR EMBL; JRUQ01000007; KGT95733.1; -; Genomic_DNA.
DR RefSeq; WP_034887974.1; NZ_JRUQ01000007.1.
DR AlphaFoldDB; A0A0A4AD04; -.
DR STRING; 371042.NG99_02260; -.
DR eggNOG; COG2226; Bacteria.
DR OrthoDB; 108476at2; -.
DR Proteomes; UP000030351; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR048647; RlmA_N.
DR InterPro; IPR016718; rRNA_m1G-MeTrfase_A_prd.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43460:SF1; METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43460; METHYLTRANSFERASE; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR Pfam; PF21302; RlmA_N; 1.
DR PIRSF; PIRSF018249; MyrA_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR018249-1};
KW Methyltransferase {ECO:0000313|EMBL:KGT95733.1};
KW S-adenosyl-L-methionine {ECO:0000256|PIRSR:PIRSR018249-2};
KW Transferase {ECO:0000313|EMBL:KGT95733.1};
KW Zinc {ECO:0000256|PIRSR:PIRSR018249-1}.
FT DOMAIN 3..46
FT /note="23S rRNA (guanine(745)-N(1))-methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21302"
FT DOMAIN 88..197
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
FT BINDING 5
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 21
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 25
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 67
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 96..97
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 186
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
SQ SEQUENCE 281 AA; 31592 MW; 818927C836BAAF89 CRC64;
MSYLCPLCHQ PLLPEAAVWR CANRHQFDRA KEGYVNLLPV QHKRSKQPGD SADMMLARRE
FLDAGHYQPL QQKVCEIFER ILPATASGVL DIGCGEGYYT HAVANRLQAR GETAVHGLDV
SKVAVRFGAK RYHNVEFCVA SSHRLPFAAG QFDAVLRIYA PCKAEELARV VKERGYVLTV
TPGPRHLIQF KALIYQDVKL HDETPEEMAG FELVEQHSLN YPLRLNSEES AALLQMTPFA
WRARPEVWGV LATTTAFDCE TDFTLRLWQR NATQGVTAAA P
//
