ID A0A0A5G9X2_9BACI Unreviewed; 436 AA.
AC A0A0A5G9X2;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=UDP-N-acetyl-D-galactosamine dehydrogenase {ECO:0000313|EMBL:KGX89961.1};
GN ORFNames=N781_08740 {ECO:0000313|EMBL:KGX89961.1};
OS Pontibacillus halophilus JSM 076056 = DSM 19796.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX NCBI_TaxID=1385510 {ECO:0000313|EMBL:KGX89961.1, ECO:0000313|Proteomes:UP000030528};
RN [1] {ECO:0000313|EMBL:KGX89961.1, ECO:0000313|Proteomes:UP000030528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSM 076056 {ECO:0000313|EMBL:KGX89961.1,
RC ECO:0000313|Proteomes:UP000030528};
RA Huang J., Wang G.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGX89961.1}.
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DR EMBL; AVPE01000018; KGX89961.1; -; Genomic_DNA.
DR RefSeq; WP_026801611.1; NZ_AVPE01000018.1.
DR AlphaFoldDB; A0A0A5G9X2; -.
DR STRING; 1385510.GCA_000425205_03418; -.
DR eggNOG; COG0677; Bacteria.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000030528; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030528}.
FT DOMAIN 322..423
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 436 AA; 48733 MW; 6515E03A0960FC9C CRC64;
MDAISELKAN FEKLSVVGLG YVGLPLAIEF SKVFNVVGFD INEGKILNYN NGIDVTNEVG
NDAIKQTSCT FTSDEDYLKE CKVHIVSVPT PINSDKTPNL NPVIEATKIV GRNMKKGSVI
VYESTVYPGT TEEICVPILE KISGLKFNID FHIGYSPERI NPGDKVNTLT KIKKVVSGSS
GEILEFVAQM YESIIEAGVH RAENIKVAEA SKIVENSQRD INIAFMNELS MVFNRMEIDT
SAVLEAAGTK WNFMRFTPGL VGGHCIGVDP YYFIYKAEQL GYHSQIILSG RKINDSMGAY
VANNVIKCII KNDKNVKGAR VAILGVTFKE NVADVRNSKV FDVVNELLDY GVEVLVCDPK
ANKEEVYNEY NLNLQEFGEL KDIDVVIAAV NHDEYKELNI DSFIELFKEG KPILFDLKKA
YEKNDYIDRG FDYWSL
//
