ID A0A0A5GD51_9BACI Unreviewed; 220 AA.
AC A0A0A5GD51;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=N781_05495 {ECO:0000313|EMBL:KGX91141.1};
OS Pontibacillus halophilus JSM 076056 = DSM 19796.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX NCBI_TaxID=1385510 {ECO:0000313|EMBL:KGX91141.1, ECO:0000313|Proteomes:UP000030528};
RN [1] {ECO:0000313|EMBL:KGX91141.1, ECO:0000313|Proteomes:UP000030528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSM 076056 {ECO:0000313|EMBL:KGX91141.1,
RC ECO:0000313|Proteomes:UP000030528};
RA Huang J., Wang G.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGX91141.1}.
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DR EMBL; AVPE01000011; KGX91141.1; -; Genomic_DNA.
DR RefSeq; WP_026800889.1; NZ_AVPE01000011.1.
DR AlphaFoldDB; A0A0A5GD51; -.
DR STRING; 1385510.GCA_000425205_02559; -.
DR eggNOG; COG0693; Bacteria.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000030528; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030528};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000313|EMBL:KGX91141.1}.
FT DOMAIN 22..217
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 220 AA; 23783 MW; 21F7F1AB8BA66814 CRC64;
MAKHVLMVVT NHSELAEGIQ TGVWLSEFAE AYNEFKANNF NVTVASPSGG LAPVDPGSVD
ESTPQELLER KAMLEQTVSL NNIDASTYDA IFLPGGHGTM FDLPKSEKLK EVLQDLFERG
KPVAAVCHGP AGLVEAKLSN GQPLVAGRKV NAFTNPEEAD TTLDKHMPFL LETKLRELGA
IYVAAPNWNA HVEVDGNLIT GQNPQSTMAV ANEFVKQLQD
//
