ID A0A0A5GNN0_9BACI Unreviewed; 274 AA.
AC A0A0A5GNN0;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Competence protein ComER {ECO:0000313|EMBL:KGX93559.1};
GN ORFNames=N781_11055 {ECO:0000313|EMBL:KGX93559.1};
OS Pontibacillus halophilus JSM 076056 = DSM 19796.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pontibacillus.
OX NCBI_TaxID=1385510 {ECO:0000313|EMBL:KGX93559.1, ECO:0000313|Proteomes:UP000030528};
RN [1] {ECO:0000313|EMBL:KGX93559.1, ECO:0000313|Proteomes:UP000030528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSM 076056 {ECO:0000313|EMBL:KGX93559.1,
RC ECO:0000313|Proteomes:UP000030528};
RA Huang J., Wang G.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pyrroline-5-carboxylate reductase family.
CC {ECO:0000256|ARBA:ARBA00005525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGX93559.1}.
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DR EMBL; AVPE01000002; KGX93559.1; -; Genomic_DNA.
DR RefSeq; WP_026802137.1; NZ_KE384328.1.
DR AlphaFoldDB; A0A0A5GNN0; -.
DR STRING; 1385510.GCA_000425205_01120; -.
DR eggNOG; COG0345; Bacteria.
DR OrthoDB; 9805754at2; -.
DR Proteomes; UP000030528; Unassembled WGS sequence.
DR GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:InterPro.
DR GO; GO:0006561; P:proline biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 1.10.3730.10; ProC C-terminal domain-like; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR028939; P5C_Rdtase_cat_N.
DR InterPro; IPR029036; P5CR_dimer.
DR InterPro; IPR000304; Pyrroline-COOH_reductase.
DR PANTHER; PTHR11645:SF51; COME OPERON PROTEIN 4; 1.
DR PANTHER; PTHR11645; PYRROLINE-5-CARBOXYLATE REDUCTASE; 1.
DR Pfam; PF03807; F420_oxidored; 1.
DR Pfam; PF14748; P5CR_dimer; 1.
DR PIRSF; PIRSF000193; Pyrrol-5-carb_rd; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00521; P5CR; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|PIRSR:PIRSR000193-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030528}.
FT DOMAIN 3..97
FT /note="Pyrroline-5-carboxylate reductase catalytic N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF03807"
FT DOMAIN 159..262
FT /note="Pyrroline-5-carboxylate reductase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF14748"
FT BINDING 6..11
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000256|PIRSR:PIRSR000193-1"
SQ SEQUENCE 274 AA; 30450 MW; 6AC407F999C2AA6C CRC64;
MKWGIIGTGN MGRMLAEVWI EKQVVKPEDL YVTNRNLDKA IGLQALYREI TIVESVEELA
EHADVLFICT KPLDIHPLLV RMSPYLTKQQ CLVSITSPYS VEELEELVPC QVARIIPSIT
NRAHAGVSLV TYGSGVSPVM KAYLEQSVKL YSTPLNIKEE ITRVASDIVS CGPAFYSFVT
QKFVEAATSE TEISKDEATI MATEMLIGLG KLLEEGHYTL KTLQEKVSVK GGVTGEGIRV
MEKEMATVFH HVIQATHDKY AEDKDKIEGQ RTTT
//
