GenomeNet

Database: UniProt
Entry: A0A0A6F1W2_9SPHN
LinkDB: A0A0A6F1W2_9SPHN
Original site: A0A0A6F1W2_9SPHN 
ID   A0A0A6F1W2_9SPHN        Unreviewed;       494 AA.
AC   A0A0A6F1W2;
DT   04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=NI18_21225 {ECO:0000313|EMBL:KHA62744.1};
OS   Sphingomonas sp. Ant20.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=104605 {ECO:0000313|EMBL:KHA62744.1};
RN   [1] {ECO:0000313|EMBL:KHA62744.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ant20 {ECO:0000313|EMBL:KHA62744.1};
RA   Ronca S., Frossard A., Guerrero L.D., Makhalanyane T.P.,
RA   Aislabie J.M., Cowan D.A.;
RT   "Draft Genome Sequence of Spingomonas sp. strain Ant20, isolated from
RT   oil-polluted soil near Scott Base, Antarctica.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KHA62744.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; JRVI01000298; KHA62744.1; -; Genomic_DNA.
DR   RefSeq; WP_037533336.1; NZ_JRVI01000298.1.
DR   EnsemblBacteria; KHA62744; KHA62744; NI18_21225.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      190    342       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      402    471       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     198    205       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   494 AA;  55212 MW;  92DAAD80DBC7CF1C CRC64;
     MTNWQGSTVH ASEAEKAWDR VRSSLRESAG ARLFEQWLKP IELIPSDDEE SIRLALPSAF
     MTNWVRNHYA DRLALEFRQI LPQVRTVQIE TRRPGPKPVL LVMPTPAETL DRDTAAAAVE
     PAQVPVKFGV DPSLKPAPAP AARPVPAYDT VIPERPPLDP RYTFDRFVVD ASNKVAFNAA
     KVLAEPGPVR FSPLFLHSNT GQGKTHLMHA IGHAFLAANP HAVVLCMSAE RFMYDFVAAM
     RARDTHAFKR RLRGADLLLI DDLQFIAGKD ATQEEFFHTI NEIMTAGKRL VISADRCPQA
     LEGVESRIIS RMAVGLVADI KAPDLLLRRT ILDRKLVDLP DLRVPTDVLD LIASRIHANI
     RELEGALNRV IAYAQLTGET IDLEFAIATL GEVLRGAQKR VTIDEIQKLV TAHFELKPLD
     MISARRARAV ARPRQIAMYL AKRLTTRSLP EIGRKFGGRD HSTVIHAVRK ITELRDQDRD
     IDAAVRVLMR ELEG
//
DBGET integrated database retrieval system