ID A0A0A6UNB1_ACTUT Unreviewed; 984 AA.
AC A0A0A6UNB1;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase {ECO:0000313|EMBL:KHD76573.1};
DE EC=2.7.7.42 {ECO:0000313|EMBL:KHD76573.1};
GN ORFNames=MB27_16350 {ECO:0000313|EMBL:KHD76573.1};
OS Actinoplanes utahensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1869 {ECO:0000313|EMBL:KHD76573.1, ECO:0000313|Proteomes:UP000054537};
RN [1] {ECO:0000313|EMBL:KHD76573.1, ECO:0000313|Proteomes:UP000054537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 12052 {ECO:0000313|EMBL:KHD76573.1,
RC ECO:0000313|Proteomes:UP000054537};
RA Velasco-Bucheli B., del Cerro C., Hormigo D., Garcia J.L., Acebal C.,
RA Arroyo M., de la Mata I.;
RT "Draft genome sequence of Actinoplanes utahensis NRRL 12052.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHD76573.1}.
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DR EMBL; JRTT01000017; KHD76573.1; -; Genomic_DNA.
DR RefSeq; WP_043525446.1; NZ_JRTT01000017.1.
DR AlphaFoldDB; A0A0A6UNB1; -.
DR STRING; 1869.MB27_16350; -.
DR eggNOG; COG1391; Bacteria.
DR OrthoDB; 9759366at2; -.
DR Proteomes; UP000054537; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:KHD76573.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054537};
KW Transferase {ECO:0000313|EMBL:KHD76573.1}.
FT DOMAIN 143..304
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 329..472
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 579..819
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 843..949
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 984 AA; 106706 MW; 8B590C07FCD53306 CRC64;
MTRPTRLARY GFADNGARAT DLLGPGGLRL WDTGTQAPVD ERAAGLLDAL SRAADPNLAL
RQLHRVVESA GRGDPARAET LLGELSADDG LRRRLLAVLG ASSALGDHLV ANPEEWRTLA
TGPSGMPPEA DGGLTDLNQL TVPDLRRAYR MALLRIAAAD LTAGRGLEPT MAALSRLADE
TLSAAYAIAV AALPQSTPEP RLAVVAMGKC GGNELNYVSD VDVIFVAAGD EDLNPATTVA
ARLIEICGQV AWPVDAALRP EGSRGPLVRT LASHQAYYRR WARTWEFQAL LKARPAAGDL
ALAQEWIADL APLVWHAAER PEAVADVRDM RRRIIDNIPK KELDREIKRG SGGLRDIEFA
VQLLQLVHGR VDETLRGGGT IPALRALVTG GYVGRQDGET LLRGYRFLRG VEHRLQLQHL
KRTHTVPDDP AGLRWLAAAL GYTAVPGRDA VEAFRSDWVG HAANVRRLHV KLLYQPLLEA
VARVPAEELR MTPESARKRL EILGFADPAG ALRHLEALTG GVTRTAAIQR TLLPMLLQDF
ADAPEPDRGL LSYRQVSDKL GSTPWYLRLL RDGGPVARRL ARVLSLSRYA TDLLTRDPEA
LRLLADDAEL QPRPRESLRD GFAAAGDRHT DPGGAIAAVR ALRRRELFRL ACADILSQGG
DLAPDRPLGV DAVGVALSDV TDATLNAALR IARRARPGPD GLRFAVIGMG RLGSYEMSYP
SDADVLFVYE PPPGCPEGEA SAAAHAIAEE MRRLLNAPAP DPALGVDADL RPEGRQGSLV
RSLQAYRQYY ERWSKVWEAQ ALLRARFVCG DADLGARFET LADTKRYPDG GLTREQVVEI
RRIKARVETE RLPRGADPNT HTKLGRGGLS DVEWAVQLTQ LRHAHAIPAL RCTRTLEALA
AEAGAGVVDE ADAAELTAGW TLAAQVRNAL TLVRGRPTDQ LPRHGVELAG AVLLLGGGDP
GEFVDRYLRL TRRSRAAMER VLES
//
