ID A0A0A6YVR9_MOUSE Unreviewed; 240 AA.
AC A0A0A6YVR9;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=SURF1-like protein {ECO:0000256|RuleBase:RU363076};
DE Flags: Fragment;
GN Name=Surf1 {ECO:0000313|Ensembl:ENSMUSP00000141238.2,
GN ECO:0000313|MGI:MGI:98443};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141238.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141238.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141238.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000141238.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141238.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the MITRAC (mitochondrial translation regulation
CC assembly intermediate of cytochrome c oxidase complex) complex, that
CC regulates cytochrome c oxidase assembly.
CC {ECO:0000256|RuleBase:RU363076}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU363076}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363076}.
CC -!- SIMILARITY: Belongs to the SURF1 family.
CC {ECO:0000256|ARBA:ARBA00007165, ECO:0000256|RuleBase:RU363076}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU363076}.
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DR AlphaFoldDB; A0A0A6YVR9; -.
DR EPD; A0A0A6YVR9; -.
DR jPOST; A0A0A6YVR9; -.
DR ProteomicsDB; 314268; -.
DR Antibodypedia; 18363; 197 antibodies from 29 providers.
DR Ensembl; ENSMUST00000147110.8; ENSMUSP00000141238.2; ENSMUSG00000015790.17.
DR AGR; MGI:98443; -.
DR MGI; MGI:98443; Surf1.
DR VEuPathDB; HostDB:ENSMUSG00000015790; -.
DR GeneTree; ENSGT00530000064194; -.
DR HOGENOM; CLU_047737_4_0_1; -.
DR OMA; WYSRDVA; -.
DR ChiTaRS; Surf1; mouse.
DR Proteomes; UP000000589; Chromosome 2.
DR Bgee; ENSMUSG00000015790; Expressed in facial nucleus and 254 other cell types or tissues.
DR ExpressionAtlas; A0A0A6YVR9; baseline and differential.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR CDD; cd06662; SURF1; 1.
DR InterPro; IPR002994; Surf1/Shy1.
DR InterPro; IPR045214; Surf1/Surf4.
DR PANTHER; PTHR23427; SURFEIT LOCUS PROTEIN; 1.
DR PANTHER; PTHR23427:SF2; SURFEIT LOCUS PROTEIN 1; 1.
DR Pfam; PF02104; SURF1; 1.
DR PROSITE; PS50895; SURF1; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363076};
KW Mitochondrion {ECO:0000256|RuleBase:RU363076};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363076};
KW Proteomics identification {ECO:0007829|EPD:A0A0A6YVR9,
KW ECO:0007829|MaxQB:A0A0A6YVR9};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363076};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363076}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363076"
FT NON_TER 240
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000141238.2"
SQ SEQUENCE 240 AA; 27146 MW; 4FE117C772D10A9E CRC64;
MVCRPRRCCS STAETAAAKA EDDSFLQWFL LLIPATAFGL GTWQVQRRKW KLKLIAELES
RVMAEPIPLP ADPMELKNLE YRPVKVRGHF DHSKELYIMP RTMVDPVREA RDAGRLSSTE
SGAHVVTPFH CSDLGVTILV NRGFVPRKKV NPETRQKGQV LGEVDLVGIV RLTENRKPFV
PENSPERNHW YYRDLEAMAK ITGADPIFID ADFHSTAPGG PIGGQTRVTL RNEHMQYILT
//
