ID A0A0A6YX83_MOUSE Unreviewed; 183 AA.
AC A0A0A6YX83;
DT 04-FEB-2015, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Interleukin 1 receptor, type II {ECO:0000313|Ensembl:ENSMUSP00000141882.2};
DE Flags: Fragment;
GN Name=Il1r2 {ECO:0000313|Ensembl:ENSMUSP00000141882.2,
GN ECO:0000313|MGI:MGI:96546};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000141882.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000141882.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141882.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000141882.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000141882.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR AlphaFoldDB; A0A0A6YX83; -.
DR SMR; A0A0A6YX83; -.
DR ProteomicsDB; 359125; -.
DR Antibodypedia; 17756; 736 antibodies from 41 providers.
DR Ensembl; ENSMUST00000191671.6; ENSMUSP00000141882.2; ENSMUSG00000026073.14.
DR AGR; MGI:96546; -.
DR MGI; MGI:96546; Il1r2.
DR VEuPathDB; HostDB:ENSMUSG00000026073; -.
DR GeneTree; ENSGT01090000259985; -.
DR HOGENOM; CLU_1478345_0_0_1; -.
DR OMA; LLWWTAN; -.
DR ChiTaRS; Il1r2; mouse.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000026073; Expressed in gastrula and 83 other cell types or tissues.
DR ExpressionAtlas; A0A0A6YX83; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004910; F:interleukin-1, type II, blocking receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR004074; IL-1_rcpt_I/II-typ.
DR InterPro; IPR004077; IL-1_rcpt_II-typ.
DR InterPro; IPR041416; IL-1RAcP-like_ig.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF3; INTERLEUKIN-1 RECEPTOR TYPE 2; 1.
DR Pfam; PF18452; Ig_6; 1.
DR PRINTS; PR01539; INTRLEUKN1R2.
DR PRINTS; PR01536; INTRLKN1R12F.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A0A6YX83,
KW ECO:0007829|ProteomicsDB:A0A0A6YX83};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 35..136
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 183
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000141882.2"
SQ SEQUENCE 183 AA; 20395 MW; 79EF2357D6A3EC2D CRC64;
MFILLVLVTG VSAFTTPTVV HTGKVSESPI TSEKPTVHGD NCQFRGREFK SELRLEGEPV
VLRCPLAPHS DISSSSHSFL TWSKLDSSQL IPRDEPRMWV KGNILWILPA VQQDSGTYIC
TFRNASHCEQ MSVELKVFKN TEASLPHVSY LQISALSTTG LLVCPDLKEF ISSNADGKIQ
WYK
//
