ID A0A0A7EQY5_GOSHI Unreviewed; 435 AA.
AC A0A0A7EQY5;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Chloroplast omega-3 fatty acid desaturase {ECO:0000313|EMBL:AIY68486.1};
DE SubName: Full=Omega-3 fatty acid desaturase, chloroplastic-like isoform X1 {ECO:0000313|RefSeq:XP_016671885.1};
GN Name=FAD78-3D {ECO:0000313|EMBL:AIY68486.1};
GN Synonyms=LOC107891556 {ECO:0000313|RefSeq:XP_016671885.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|EMBL:AIY68486.1};
RN [1] {ECO:0000313|EMBL:AIY68486.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25403726; DOI=10.1186/s12870-014-0312-5;
RA Yurchenko O.P., Park S., Ilut D.C., Inmon J.J., Millhollon J.C.,
RA Liechty Z., Page J.T., Jenks M.A., Chapman K.D., Udall J.A., Gore M.A.,
RA Dyer J.M.;
RT "Genome-wide analysis of the omega-3 fatty acid desaturase gene family in
RT Gossypium.";
RL BMC Plant Biol. 14:312-312(2014).
RN [2] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [3] {ECO:0000313|RefSeq:XP_016671885.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016671885.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; KF460143; AIY68485.1; -; Genomic_DNA.
DR EMBL; KF460144; AIY68486.1; -; mRNA.
DR RefSeq; NP_001313717.1; NM_001326788.1.
DR RefSeq; XP_016671885.1; XM_016816396.1.
DR STRING; 3635.A0A0A7EQY5; -.
DR PaxDb; 3635-A0A0A7EQY5; -.
DR GeneID; 107891556; -.
DR KEGG; ghi:107891556; -.
DR OMA; PERSGPI; -.
DR OrthoDB; 4215at2759; -.
DR UniPathway; UPA00658; -.
DR Proteomes; UP000189702; Chromosome 14.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042389; F:omega-3 fatty acid desaturase activity; IBA:GO_Central.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IBA:GO_Central.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 114..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..127
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 134..389
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 435 AA; 50398 MW; 9460FDAA9C388DDA CRC64;
MESFLISKSG LKPLPRIYIR PITGLVPRNY FSKPRFLHTS KCFSDLKVTT PLKVASVEED
EEINERMHGI NKIGEQEEET IFDPAAPPPF NLADVRATIP QHCWVKDPWK SMSYVVRDVA
LVLSLAAAVV YVNNWLVWPL YWVAQGTMFW ALFVLGHDCG HGSFSNNPKL NSLVGHLLHS
FILVPYHGWR ISHRIHHQNQ GHVENDESWH PLTEKTYMSL DNNELTWRFK FPFPLLVYPF
YLWGRSPGKT GSHFDPNSEL FVPSERKDVI TSSLCWTAMA AILVGLGFTM GPMLLLKLYG
VPYWIFVIWL DFVTYMHHHG HQDKLPWYRG KEWSYIRGGL TTLDRDYGWM NNIHHDIGTH
VIHHLFPQIP HYHLIEATKA AKPVLGKYYR EPERSGPIPF YLIGVFIRSL KEDHYVSDTG
DVVYYKTDPN IFKSA
//
