ID A0A0A7FW46_9CLOT Unreviewed; 578 AA.
AC A0A0A7FW46;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Diguanylate cyclase domain protein {ECO:0000313|EMBL:AIY83086.1};
GN ORFNames=U729_2319 {ECO:0000313|EMBL:AIY83086.1};
OS Clostridium baratii str. Sullivan.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1415775 {ECO:0000313|EMBL:AIY83086.1, ECO:0000313|Proteomes:UP000030635};
RN [1] {ECO:0000313|EMBL:AIY83086.1, ECO:0000313|Proteomes:UP000030635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sullivan {ECO:0000313|EMBL:AIY83086.1};
RX PubMed=25489752; DOI=10.1016/j.meegid.2014.12.002;
RA Smith T.J., Hill K.K., Xie G., Foley B.T., Williamson C.H., Foster J.T.,
RA Johnson S.L., Chertkov O., Teshima H., Gibbons H.S., Johnsky L.A.,
RA Karavis M.A., Smith L.A.;
RT "Genomic sequences of six botulinum neurotoxin-producing strains
RT representing three clostridial species illustrate the mobility and
RT diversity of botulinum neurotoxin genes.";
RL Infect. Genet. Evol. 30:102-113(2014).
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DR EMBL; CP006905; AIY83086.1; -; Genomic_DNA.
DR RefSeq; WP_039315118.1; NZ_CP006905.1.
DR AlphaFoldDB; A0A0A7FW46; -.
DR STRING; 1561.NPD11_701; -.
DR KEGG; cbv:U729_2319; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_000445_92_5_9; -.
DR OrthoDB; 9804747at2; -.
DR Proteomes; UP000030635; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000030635}.
FT DOMAIN 1..58
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 119..190
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 191..244
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 273..398
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 387..578
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 578 AA; 65913 MW; F1E10DDAFEE4FFAC CRC64;
MNLIDILLEN IPFAILIANK DSKVEMVNTK FCEMLHLSKE DILKKHIEYL LDKIYSNENI
KFNRDIDLGS KSVKEYSVYD KVVEVHVVKV NDYDSKISSI VTLIDVTWRV GAKKEIIKQK
NMLNSIIDAI PESIFFKDVN SKYLGCNLAF EKLFDVKREE IIGKGNEILA LSKEEAENFV
AKDKEVIETG KCIKVESIHT YKNGKVFLED IKAPIFGEEN EIIGVVGTSR DITERKKLED
KLTYLSYRDK LTGLYNRTYF DKVSKEYNKN KEDIISIIMG DMNGLKIVND SLGHLEGDRF
IVEIAKIIKK VVKDKGEVVR WGGDEIVVIL KGIDKDKAIE ISKNISNKCL LANHKPVPLS
ISLGVSSGKG KSIDELITEA EKEVYKNKLL NDVNVRKATI NSIKRNIYNN ADTKKRTRRM
MKLANKIGEE MNLSKNQMSN LRLVVKLHDI GKIGISYEIL EKGNNLTKEE IELIKLHTEK
GYRILQADKD LSHIASAVLT HHERWDGKGY PLGLSGNNIP FCARVVYLLN AYDYMVNGKS
EKISEEEAME RIKKDSGKKF DPSLVKVFLR VLKNLKCK
//
