ID A0A0A8B4H6_9ACTN Unreviewed; 209 AA.
AC A0A0A8B4H6;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=thiamine diphosphokinase {ECO:0000256|ARBA:ARBA00013245};
DE EC=2.7.6.2 {ECO:0000256|ARBA:ARBA00013245};
GN ORFNames=JI75_06235 {ECO:0000313|EMBL:AJC12310.1};
OS Berryella intestinalis.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Berryella.
OX NCBI_TaxID=1531429 {ECO:0000313|EMBL:AJC12310.1, ECO:0000313|Proteomes:UP000031121};
RN [1] {ECO:0000313|Proteomes:UP000031121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=68-1-3 {ECO:0000313|Proteomes:UP000031121};
RA Looft T., Bayles D.O., Stanton T.B.;
RT "Coriobacteriaceae sp. complete genome.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJC12310.1, ECO:0000313|Proteomes:UP000031121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=68-1-3 {ECO:0000313|EMBL:AJC12310.1,
RC ECO:0000313|Proteomes:UP000031121};
RX PubMed=26450725;
RA Looft T., Bayles D.O., Alt D.P., Stanton T.B.;
RT "Complete Genome Sequence of Coriobacteriaceae Strain 68-1-3, a Novel
RT Mucus-Degrading Isolate from the Swine Intestinal Tract.";
RL Genome Announc. 3:e01143-15(2015).
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DR EMBL; CP009302; AJC12310.1; -; Genomic_DNA.
DR RefSeq; WP_039689531.1; NZ_CP009302.1.
DR AlphaFoldDB; A0A0A8B4H6; -.
DR STRING; 1531429.JI75_06235; -.
DR KEGG; cbac:JI75_06235; -.
DR HOGENOM; CLU_044237_1_2_11; -.
DR OrthoDB; 9804377at2; -.
DR Proteomes; UP000031121; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0030975; F:thiamine binding; IEA:InterPro.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0006772; P:thiamine metabolic process; IEA:InterPro.
DR CDD; cd07995; TPK; 1.
DR Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR InterPro; IPR006282; Thi_PPkinase.
DR InterPro; IPR007373; Thiamin_PyroPKinase_B1-bd.
DR InterPro; IPR007371; TPK_catalytic.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR NCBIfam; TIGR01378; thi_PPkinase; 1.
DR PANTHER; PTHR41299; THIAMINE PYROPHOSPHOKINASE; 1.
DR PANTHER; PTHR41299:SF1; THIAMINE PYROPHOSPHOKINASE; 1.
DR Pfam; PF04265; TPK_B1_binding; 1.
DR Pfam; PF04263; TPK_catalytic; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AJC12310.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031121};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 29..123
FT /note="Thiamin pyrophosphokinase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04263"
FT DOMAIN 149..200
FT /note="Thiamin pyrophosphokinase thiamin-binding"
FT /evidence="ECO:0000259|Pfam:PF04265"
SQ SEQUENCE 209 AA; 22647 MW; F72B20707FAEEEE3 CRC64;
MSVCAVVAAS DFNADHFKSL DDQGFFDEVY AVDGGWAHLV SLGRKADMAL GDFDSLGYVP
DCARVSKHPV MKDQSDLELA LERVKTRRYS EVFVYGALGG RLDHTLANLQ LFAKFAEEGM
DVVAIDLGSA LRVLVGPDAF DLPNLPSGTV SVFSASDEAH GVIERGLRYA FNDETLTNRT
SRGLSNELMG EPAMVGLEKG SIFVFYPLG
//
