ID   A0A0A8EGL3_9ACTN        Unreviewed;       338 AA.
AC   A0A0A8EGL3;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Sphingomyelin phosphodiesterase {ECO:0000313|EMBL:AJC54612.1};
GN   ORFNames=GZL_02018 {ECO:0000313|EMBL:AJC54612.1};
OS   Streptomyces sp. 769.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1262452 {ECO:0000313|EMBL:AJC54612.1, ECO:0000313|Proteomes:UP000031113};
RN   [1] {ECO:0000313|EMBL:AJC54612.1, ECO:0000313|Proteomes:UP000031113}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=769 {ECO:0000313|EMBL:AJC54612.1,
RC   ECO:0000313|Proteomes:UP000031113};
RA   Du Q., Wang Q., Li Q., Wang L., Zhang Z., Ren J., Wang J., Wang M.;
RT   "Complete Genome Sequence of Streptomyces gongzhulingensis.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003987; AJC54612.1; -; Genomic_DNA.
DR   RefSeq; WP_039630848.1; NZ_CP003987.1.
DR   AlphaFoldDB; A0A0A8EGL3; -.
DR   KEGG; stre:GZL_02018; -.
DR   HOGENOM; CLU_033415_0_0_11; -.
DR   Proteomes; UP000031113; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:InterPro.
DR   CDD; cd09078; nSMase; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR038772; Sph/SMPD2-like.
DR   InterPro; IPR017766; Sphingomyelinase/PLipase_C.
DR   NCBIfam; TIGR03395; sphingomy; 1.
DR   PANTHER; PTHR16320:SF23; SPHINGOMYELINASE DDB_G0288017; 1.
DR   PANTHER; PTHR16320; SPHINGOMYELINASE FAMILY MEMBER; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           32..338
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039692050"
FT   DOMAIN          82..332
FT                   /note="Endonuclease/exonuclease/phosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF03372"
SQ   SEQUENCE   338 AA;  36185 MW;  663F0EC094EC14E3 CRC64;
     MPHSALRTSR VAAIAVALAA TLAVASPTVS AVSPSAAAGP TGSPSAASAP RLRVLTYNTF
     LMSKNLYPNW GQDHRAQAIA SADFFHGNDV VVLQEAFDNS SSDALKSQAA AEYPHQTPVV
     GRSRSGWDAT GGAYSAVTPE DGGVTLLSKW PVLRKEQYIY KDACGSDSFS NKGFVYAVLD
     VNGTKVHVVG THTQSTDSGC KAGEAAADRA KQLKEMDAFL DAKNIPADEE IMVAGDMNTD
     SHGSEYDALL ANADLAPADS RTGHPYSFDT QENSIAAYRY PNDPREDLDY VLFRNGHARP
     TGWRNTVIKE QSAPWTVSSW GKDYTYTNLS DHYPVVSG
//