ID A0A0A8HLT8_STAHY Unreviewed; 497 AA.
AC A0A0A8HLT8;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000256|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000256|HAMAP-Rule:MF_00212,
GN ECO:0000313|EMBL:RIO47270.1};
GN ORFNames=BUZ57_01940 {ECO:0000313|EMBL:RIO47270.1}, GLV83_00140
GN {ECO:0000313|EMBL:NJI30103.1};
OS Staphylococcus hyicus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=1284 {ECO:0000313|EMBL:RIO47270.1, ECO:0000313|Proteomes:UP000285625};
RN [1] {ECO:0000313|EMBL:RIO47270.1, ECO:0000313|Proteomes:UP000285625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SNUC 5959 {ECO:0000313|EMBL:RIO47270.1,
RC ECO:0000313|Proteomes:UP000285625};
RX PubMed=28066335; DOI=.3389/fmicb.2016.01990;
RA Naushad S., Barkema H.W., Luby C., Condas L.A., Nobrega D.B., Carson D.A.,
RA De Buck J.;
RT "Comprehensive Phylogenetic Analysis of Bovine Non-aureus Staphylococci
RT Species Based on Whole-Genome Sequencing.";
RL Front. Microbiol. 7:1990-1990(2016).
RN [2] {ECO:0000313|EMBL:NJI30103.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1380 {ECO:0000313|EMBL:NJI30103.1};
RA Rhoads D., Shwani A., Adkins P., Calcutt M., Middleton J.;
RT "Whole genome comparisons of Staphylococcus agnetis isolates from cattle
RT and chickens.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001139, ECO:0000256|HAMAP-
CC Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005012, ECO:0000256|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000256|HAMAP-
CC Rule:MF_00212}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIO47270.1}.
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DR EMBL; WMFP01000003; NJI30103.1; -; Genomic_DNA.
DR EMBL; QXVO01000004; RIO47270.1; -; Genomic_DNA.
DR RefSeq; WP_039643654.1; NZ_WMFP01000003.1.
DR AlphaFoldDB; A0A0A8HLT8; -.
DR STRING; 1284.SHYC_00875; -.
DR GeneID; 41072029; -.
DR KEGG; shu:SHYC_00875; -.
DR HOGENOM; CLU_028151_0_0_9; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000285625; Unassembled WGS sequence.
DR Proteomes; UP000606275; Unassembled WGS sequence.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR NCBIfam; NF040844; Lac_Quin_Ox_NO; 1.
DR NCBIfam; TIGR01320; mal_quin_oxido; 1.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|HAMAP-Rule:MF_00212};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW Rule:MF_00212};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, ECO:0000256|HAMAP-
KW Rule:MF_00212};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532, ECO:0000256|HAMAP-
KW Rule:MF_00212}.
SQ SEQUENCE 497 AA; 56327 MW; 62C0A551C71289A2 CRC64;
MSNQSEPRNI IVVGAGVLST TFSSMIKELE PNWNIKLYER LDRPGLESSN ERHNAGTGHA
ALCELNYTVL QPDGSIDIEK AKHINEEFEI SKQFWGFLVK NKNISNPREF INPLPHISFV
RGVNNRKFLK DRYEAMKQSP MFDNIEYTED IEVMRKWMPL MMKGRDASDI MAASKIDEGT
DVNFGELTRK MTSNIEAHDN AEVKYNHEVI DFMQREDKKW EVKIRNRNSG KVFTEIAHHV
FIGAGGGAIP LLQKTGIPES KNLGGFPITG QFLTCTNPEV VEEHGVKVYG KEPPGTPPMT
VPHLDTRYIN GEKTLLFGPF ASVGPKFLKN GSNLDLFRSV KPYNIMTLLA SAAKNLPLIK
YSFDQILMTK EGCMNHLRTF YPEARDEDWE LYTAGKRVQV IKDTEEYGKG FIQFGTEVVN
SQDHTVIALL GESPGASTSV SVALEVLEKN FPELTSEWTP KIQKMIPSYG KSLIEDEALM
RKTRKQTSKD LELNYYE
//
