ID A0A0A8L3N3_9SACH Unreviewed; 538 AA.
AC A0A0A8L3N3;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=KLDO_g1955 {ECO:0000313|EMBL:CDO93664.1};
OS Kluyveromyces dobzhanskii CBS 2104.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1427455 {ECO:0000313|EMBL:CDO93664.1, ECO:0000313|Proteomes:UP000031516};
RN [1] {ECO:0000313|EMBL:CDO93664.1, ECO:0000313|Proteomes:UP000031516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS2104 {ECO:0000313|Proteomes:UP000031516};
RA Nystedt B., Astrom S.;
RT "The genome of Kluyveromyces dobzhanskii.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO93664.1}.
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DR EMBL; CCBQ010000026; CDO93664.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0A8L3N3; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000031516; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..62
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 126..169
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 169..211
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 51..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 538 AA; 60211 MW; 515E88A5DF28B08B CRC64;
MEGDSSSKFV PEYRRTNFKN KGRFSADELR RRRDVQQVEL RKVKRDEALA KRRNFNAPVG
NDSEDEDEDD DDRDSSFYRQ LQQELPGMLE QIHSNDLQQQ LAVTVKFRQV LSREHRPPID
LVISTGVVPT LVQFMSENQP EMLQLEAAWA LTNIASGTSE QTRVVVDAGA VPLFIQLLYS
NSVEVKEQAI WALGNVAGDS TDYRDYVLQC GAMQPILYLF ELNKTSLIRT ATWTLSNLCR
GKKPQPDWTI VSQALPTLSK LIYSMDTETL VDACWAISYL SDGPVNSIQA VVDARIPKRL
VELLSHQSTL VQTPALRAVG NIVTGNDLQT QIVINCGALA ALRNLLASPK ESIRKEGCWT
ISNITAGNTE QIQAVIDANL IPPLIRLLET AEYKTKKEAC WAISNASSGG LHKPEIIRYL
VSQGCIKPLC DLLEIADNRI IEVTLDAIEN ILKMGEMDRE IRGIAVNENA DFIEKAGGME
KIFNLQSNAN EKIYEKAFKI IEKYFSDEDD VVDESMAPQT AGNTFGFGSN VNQQFNFN
//
