ID A0A0A8WK74_TOBAC Unreviewed; 285 AA.
AC A0A0A8WK74;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Aquaporin PIP2 3b {ECO:0000313|EMBL:DAA64676.1};
DE SubName: Full=Aquaporin PIP2-1-like {ECO:0000313|RefSeq:XP_016436646.1};
DE SubName: Full=Aquaporin PIP2-5t {ECO:0000313|EMBL:DAC84304.1};
GN Name=LOC107762778 {ECO:0000313|RefSeq:XP_016436646.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:DAA64676.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|EMBL:DAA64676.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25486887;
RA Ma X., Shatil-Cohen A., Ben-Dor S., Wigoda N., Perera I.Y., Im Y.J.,
RA Diminshtein S., Yu L., Boss W.F., Moshelion M., Moran N.;
RT "Do phosphoinositides regulate membrane water permeability of tobacco
RT protoplasts by enhancing the aquaporin pathway?";
RL Planta 0:0-0(2014).
RN [3] {ECO:0000313|RefSeq:XP_016436646.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (FEB-2017) to UniProtKB.
RN [4] {ECO:0000313|EMBL:DAC84304.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=32517797;
RA De Rosa A., Watson-Lazowski A., Evans J.R., Groszmann M.;
RT "Genome-wide identification and characterisation of Aquaporins in Nicotiana
RT tabacum and their relationships with other Solanaceae species.";
RL BMC Plant Biol. 20:0-266(2020).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
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DR EMBL; BK008508; DAA64676.1; -; mRNA.
DR EMBL; BK011409; DAC84304.1; -; mRNA.
DR RefSeq; NP_001311701.1; NM_001324772.1.
DR RefSeq; XP_016436646.1; XM_016581160.1.
DR STRING; 4097.A0A0A8WK74; -.
DR PaxDb; 4097-A0A0A8WK74; -.
DR GeneID; 107762778; -.
DR KEGG; nta:107762778; -.
DR OMA; IRTIEFW; -.
DR OrthoDB; 3236018at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR NCBIfam; TIGR00861; MIP; 1.
DR PANTHER; PTHR45687; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR45687:SF102; PLASMA INTRINSIC PROTEIN 2-1; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 285 AA; 30486 MW; 1A7217B2A8FA59DF CRC64;
MAKDIEYGTD QYAPNKDYQD PPPAPLIDAE ELGKWSFYRA IIAEFIATLL FLYITVLTVI
GYKSQSDTKH NGDECGGVGI LGIAWAFGGM IFVLVYCTAG ISGGHINPAV TFGLFLARKI
SLARAVMYMI AQCLGAICGC GLVKAFQKSY YVRYGGGANE LATGYSTGTG LAAEIIGTFV
LVYTVFSATD PKRNARDSHV PVLAPLPIGF AVFMVHLATI PITGTGINPA RSFGAAVIYG
KDKAWDDQWI FWVGPLIGAA IAALYHQYIL RAGAVKALGS FRSNA
//
